富马酸二甲酯治疗大疱性类天疱疮成功：一例报告。
Successful management of bullous pemphigoid with dimethyl fumarate therapy: A case report.
作者信息
Bilgic-Temel Aslı, Das Shilpa, Murrell Dedee F
机构信息
St George Hospital, Department of Dermatology, University of New South Wales, Sydney, Australia.
Faculty of Medicine, University of New South Wales, Sydney, Australia.
出版信息
Int J Womens Dermatol. 2019 Feb 22;5(3):179-180. doi: 10.1016/j.ijwd.2019.02.001. eCollection 2019 Jul.
A 69-year-old woman affected by multiple sclerosis for 35 years was diagnosed with bullous pemphigoid (BP) and treated successfully with dimethyl fumarate (DMF) at a dose of 120 mg twice per day for 7 days and then increased to 240 mg twice per day after first-line therapies of BP. DMF is now under evaluation with an investigator-initiated prospective controlled trial in patients with BP to determine the efficacy and safety of adjuvant DMF. To our knowledge, this is the first case of BP successfully treated with DMF in the literature.
一名患多发性硬化症35年的69岁女性被诊断为大疱性类天疱疮（BP），接受富马酸二甲酯（DMF）治疗并取得成功，初始剂量为每日两次，每次120毫克，持续7天，之后在BP一线治疗后增加至每日两次，每次240毫克。目前，一项由研究者发起的针对BP患者的前瞻性对照试验正在评估DMF，以确定辅助使用DMF的疗效和安全性。据我们所知，这是文献中首例用DMF成功治疗BP的病例。
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