Gurumurthy Radhika Yajaman, Shankar N Siddharth, Mohan Raj C S, Sriram N
Department of Histopathology, Bhagavan Pathology Laboratory, Mysore, Karnataka, India.
Indian J Pathol Microbiol. 2019 Jul-Sep;62(3):464-466. doi: 10.4103/IJPM.IJPM_305_18.
Cloacogenic carcinoma also known as basaloid squamous cell carcinoma is a rare anorectal tumor presenting with varied histomorphology. In this case report, we describe a case of 58-year-old man presenting with bleeding per rectum and pain. A polypoidal tumor was noted in anal canal which on microscopy was diagnosed to be cloacogenic carcinoma with transitional carcinoma-like, basaloid and mucinous patterns. An unusual finding in the present case was the presence of signet ring cells in the mucinous areas. A thorough knowledge of the wide histomorphological spectrum of the tumor and a limited IHC panel are crucial for the diagnosis. Here, we also present a review of literature and describe in detail the origin and histopathological features of the tumor.
泄殖腔源癌也称为基底样鳞状细胞癌，是一种罕见的肛肠肿瘤，具有多种组织形态学表现。在本病例报告中，我们描述了一名58岁男性，表现为直肠出血和疼痛。在肛管发现一个息肉样肿瘤，显微镜检查诊断为具有移行癌样、基底样和黏液样模式的泄殖腔源癌。本病例的一个不寻常发现是黏液区域存在印戒细胞。全面了解该肿瘤广泛的组织形态学谱以及有限的免疫组化指标对于诊断至关重要。在此，我们还对文献进行了综述，并详细描述了该肿瘤的起源和组织病理学特征。
