Mitra Subhashis, Jhunjhunwala Amiya, Mukherjee Paromita
Department of Pathology, AMRI Hospitals, Kolkata, West Bengal, India.
Indian J Pathol Microbiol. 2019 Jul-Sep;62(3):467-469. doi: 10.4103/IJPM.IJPM_412_18.
Histiocytic sarcoma is a rare malignant neoplasm that demonstrates mature histiocytic traits as characterized by immunohistochemistry. We report a case of extranodal histiocytic sarcoma (ENHS) of colon in a 56-year-old man presenting with gastrointestinal symptoms. Radiological findings were indicative of lymphoma or diffuse metastatic disease in colon. Histopathology of colectomy specimen was suggestive of ENHS, and immunohistochemical studies confirmed the uncommon diagnosis. The patient refused further therapy and succumbed to systemic complications of metastatic disease within a month of diagnosis. There have only been seven previous reports in world literature of ENHS involving large intestine.
组织细胞肉瘤是一种罕见的恶性肿瘤，经免疫组织化学鉴定具有成熟组织细胞特征。我们报告一例56岁男性结肠结外组织细胞肉瘤（ENHS），患者表现出胃肠道症状。影像学检查结果提示结肠淋巴瘤或弥漫性转移性疾病。结肠切除标本的组织病理学检查提示为ENHS，免疫组织化学研究证实了这一罕见诊断。患者拒绝进一步治疗，在诊断后一个月内死于转移性疾病的全身并发症。世界文献中此前仅有7例涉及大肠的ENHS报告。
