Department of Dermatology, Dongguk University Ilsan Hospital, College of Medicine, Dongguk University, Goyang, Korea.
Dermatol Ther. 2019 Sep;32(5):e13037. doi: 10.1111/dth.13037. Epub 2019 Aug 8.
Frontal fibrosing alopecia (FFA) is an inflammatory disorder characterized by scarring alopecia of the frontotemporal scalp, thinning or loss of facial hair, and facial papules. Prompt treatment is essential to prevent permanent hair loss. Although studies have reported the efficacy of oral retinoids (isotretinoin and acitretin) in FFA treatment, a therapeutic role for alitretinoin is known only for lichen planus and not for FFA. Herein, we report a case of FFA accompanied with lichen planus that responded well to treatment with alitretinoin.
额部纤维性脱发（FFA）是一种炎症性疾病，其特征为额颞部头皮瘢痕性脱发、面毛变细或缺失，以及面部丘疹。及时治疗对于预防永久性脱发至关重要。尽管有研究报道了口服维 A 酸类药物（异维 A 酸和阿维 A 酯）在 FFA 治疗中的疗效，但阿利维 A 仅已知对扁平苔藓有效，而对 FFA 无效。在此，我们报告了一例 FFA 伴扁平苔藓的病例，阿利维 A 治疗效果良好。
