Hemphill Andrew, Müller Norbert, Müller Joachim
Institute of Parasitology, University of Berne, Länggass-Strasse 122, 3012 Berne, Switzerland.
Pathogens. 2019 Jul 29;8(3):116. doi: 10.3390/pathogens8030116.
Protozoan parasites can infect the human intestinal tract causing serious diseases. In the following article, we focused on the three most prominent intestinal protozoan pathogens, namely, , , and . Both and colonize the duodenum, jejunum, and ileum and are the most common causative agents of persistent diarrhea (i.e., cryptosporidiosis and giardiasis). colonizes the colon and, unlike the two former pathogens, may invade the colon wall and disseminate to other organs, mainly the liver, thereby causing life-threatening amebiasis. Here, we present condensed information concerning the pathobiology of these three diseases.
原生动物寄生虫可感染人类肠道,引发严重疾病。在以下文章中,我们聚焦于三种最突出的肠道原生动物病原体,即隐孢子虫、贾第虫和溶组织内阿米巴。隐孢子虫和贾第虫均定殖于十二指肠、空肠和回肠,是持续性腹泻(即隐孢子虫病和贾第虫病)最常见的病原体。溶组织内阿米巴定殖于结肠,与前两种病原体不同,它可能侵入结肠壁并扩散至其他器官,主要是肝脏,从而引发危及生命的阿米巴病。在此,我们呈现有关这三种疾病病理生物学的简要信息。