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使用Halcyon™ 2.0进行全乳及淋巴结照射,采用自动多等中心治疗投送和每日千伏级锥形束计算机断层扫描。

Whole Breast and Lymph Node Irradiation using Halcyon™ 2.0 Utilizing Automatic Multi-isocenter Treatment Delivery and Daily Kilovoltage Cone-beam Computed Tomography.

作者信息

Kim Michele M, Kennedy Chris, Scheuermann Ryan, Freedman Gary, Li Taoran

机构信息

Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

出版信息

Cureus. 2019 May 24;11(5):e4744. doi: 10.7759/cureus.4744.

DOI:10.7759/cureus.4744
PMID:31363426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6663281/
Abstract

The Halcyon is a newly introduced platform to provide a simplified high-throughput workflow. A substantial fraction of patients treated with radiation are receiving breast irradiation. The Halcyon has a smaller maximum field size (28 x 28 cm) compared to traditional C-arm linacs, limiting treatment of larger breast fields. With the use of autofeathering and linked multiple isocenters, non-divergent beams can be used to treat whole breast with large mid-tangent separation. In this case report, a multiple isocenter whole breast treatment with nodal involvement is described with the Halcyon 2.0 platform. The patient was simulated with the same immobilization techniques as used for C-arm linac treatments. The treatment planning time was around 20-30 minutes, which is similar to traditional planning for C-arm linacs, and dosimetric analysis resulted in satisfactory dose-volume histogram (DVH) parameters that met all planning objectives. Treatment times were shorter with an average of 9:32 minutes from the beginning of imaging to the end of treatment and a total in-room time of around 15 minutes per fraction. The use of multiple isocenters for the extended treatment field created a half-beam block type field arrangement, which has been previously reported to produce superior dosimetry results at the supraclavicular-tangents junction area.

摘要

Halcyon是一个新推出的平台,旨在提供简化的高通量工作流程。接受放射治疗的患者中有很大一部分正在接受乳腺照射。与传统的C型臂直线加速器相比,Halcyon的最大射野尺寸较小(28×28 cm),限制了对较大乳腺射野的治疗。通过使用自动羽化和连接多个等中心,可以使用非发散束来治疗具有大的中间切线间距的全乳。在本病例报告中,描述了使用Halcyon 2.0平台对伴有淋巴结受累的全乳进行多等中心治疗的情况。该患者采用了与C型臂直线加速器治疗相同的固定技术进行模拟。治疗计划时间约为20 - 30分钟,这与传统的C型臂直线加速器计划相似,剂量分析得出的剂量体积直方图(DVH)参数令人满意,满足了所有计划目标。治疗时间较短,从成像开始到治疗结束平均为9分32秒,每次分割的总室内时间约为15分钟。使用多个等中心进行扩展治疗射野产生了半束遮挡型射野布置方式,此前已有报道称这种方式在锁骨上 - 切线交界区域能产生更好的剂量学结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/beb18b5d9a8e/cureus-0011-00000004744-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/667c1145730c/cureus-0011-00000004744-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/a020a33e1dbf/cureus-0011-00000004744-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/0f0e06bc6457/cureus-0011-00000004744-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/a99d2392e1cf/cureus-0011-00000004744-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/b289887cd4ae/cureus-0011-00000004744-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/8c003faef4ae/cureus-0011-00000004744-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/0de53bd571e5/cureus-0011-00000004744-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/beb18b5d9a8e/cureus-0011-00000004744-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/667c1145730c/cureus-0011-00000004744-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/a020a33e1dbf/cureus-0011-00000004744-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/0f0e06bc6457/cureus-0011-00000004744-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/a99d2392e1cf/cureus-0011-00000004744-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/b289887cd4ae/cureus-0011-00000004744-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/8c003faef4ae/cureus-0011-00000004744-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/0de53bd571e5/cureus-0011-00000004744-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/6663281/beb18b5d9a8e/cureus-0011-00000004744-i08.jpg

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本文引用的文献

1
Characterization of a prototype rapid kilovoltage x-ray image guidance system designed for a ring shape radiation therapy unit.用于环形放射治疗设备的原型千伏快速 X 射线影像引导系统的特性描述。
Med Phys. 2019 Mar;46(3):1355-1370. doi: 10.1002/mp.13396. Epub 2019 Feb 13.
2
Whole Breast Irradiation with Halcyon™ 2.0: Workflow and Efficiency of Field-in-Field Treatment with Dynamic Beam Flattening Technique and kV Cone Beam Computed Tomography.使用Halcyon™ 2.0进行全乳照射:采用动态束流平坦化技术和千伏锥形束计算机断层扫描的野中野治疗工作流程与效率
Cureus. 2018 Oct 29;10(10):e3510. doi: 10.7759/cureus.3510.
3
Review of the three-field techniques in breast cancer radiotherapy.
Treatment planning comparison of volumetric modulated arc therapy employing a dual-layer stacked multi-leaf collimator and helical tomotherapy for cervix uteri.
采用双层堆叠多叶准直器和螺旋断层放疗治疗子宫颈的容积调强弧形治疗计划比较。
Radiat Oncol. 2020 Jan 30;15(1):22. doi: 10.1186/s13014-020-1473-z.
4
Many-isocenter optimization for robotic radiotherapy.机器人放射治疗的多等中心优化。
Phys Med Biol. 2020 Feb 10;65(4):045003. doi: 10.1088/1361-6560/ab63b8.
乳腺癌放射治疗中三野技术的综述。
J BUON. 2017 May-Jun;22(3):599-605.
4
Determination of the optimal method for the field-in-field technique in breast tangential radiotherapy.乳腺切线放疗中野中野技术最佳方法的确定。
J Radiat Res. 2014 Jul;55(4):769-73. doi: 10.1093/jrr/rrt233. Epub 2014 Feb 16.
5
Technique alternatives for breast radiation oncology: Conventional radiation therapy to tomotherapy.乳腺放射肿瘤学的技术替代方案:从传统放射治疗到断层放射治疗。
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6
Performance evaluation of field-in-field technique for tangential breast irradiation.乳腺切线照射野中野技术的性能评估
Jpn J Clin Oncol. 2008 Feb;38(2):158-63. doi: 10.1093/jjco/hym167. Epub 2008 Jan 22.
7
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