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乳腺放射肿瘤学的技术替代方案:从传统放射治疗到断层放射治疗。

Technique alternatives for breast radiation oncology: Conventional radiation therapy to tomotherapy.

作者信息

Fournier-Bidoz N, Kirova Y, Campana F, El Barouky J, Zefkili S, Dendale R, Bollet M A, Mazal A, Fourquet A

机构信息

Department of Radiation Oncology, Institut Curie, 26 rue d'Ulm, Paris 75005, France.

出版信息

J Med Phys. 2009 Jul;34(3):149-52. doi: 10.4103/0971-6203.54849.

DOI:10.4103/0971-6203.54849
PMID:20098562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2807680/
Abstract

Breast conserving radiotherapy uses tangential fields and compensating wedges. This conventional approach can be improved by a field-in-field technique using the linac multi-leaf collimator (MLC). A simplified field-in-field technique that planners can easily achieve and which improves dose uniformity in the breast volume is presented here. Field junction problems are more easily solved by the use of a virtual simulation. A unique isocenter can be set at the junction between the supra-clavicular field and the breast tangential fields. However, careful quality assurance of the treatment planning system must be performed. Tomotherapy has promising clinical advantages: the ability of a tomographic image to correct for random set-up errors, a continuous cranio-caudal delivery which suppresses junction problems, the conformality of the dose distribution throughout the complex volumes formed by the lymph nodes and the breasts. Tomotherapy is a valuable recourse for complex irradiations like bilateral breast or mammary plus axillary irradiation while a field-in-field associated with a unique isocenter technique can be used for majority of the patients.

摘要

保乳放疗采用切线野和补偿楔形板。这种传统方法可通过使用直线加速器多叶准直器(MLC)的野中野技术得到改进。本文介绍了一种简化的野中野技术,计划者可轻松实现该技术,且该技术能改善乳腺体积内的剂量均匀性。通过使用虚拟模拟,野交界问题更容易解决。可在锁骨上野与乳腺切线野的交界处设置一个独特的等中心。然而,必须对治疗计划系统进行仔细的质量保证。断层放疗具有有前景的临床优势:断层图像能够校正随机摆位误差、连续的头脚方向照射可抑制交界问题、剂量分布在由淋巴结和乳腺形成的复杂体积内具有适形性。对于双侧乳腺或乳腺加腋窝照射等复杂照射,断层放疗是一种有价值的手段,而对于大多数患者,可使用与独特等中心技术相关的野中野技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/62fce5c4e16e/JMP-34-149-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/5be60ad6e904/JMP-34-149-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/63dd72626a03/JMP-34-149-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/b3e2c70c13f0/JMP-34-149-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/2b6c2224dbdf/JMP-34-149-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/f71e5a04ff28/JMP-34-149-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/62fce5c4e16e/JMP-34-149-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/5be60ad6e904/JMP-34-149-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/15b4933e4d9f/JMP-34-149-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/63dd72626a03/JMP-34-149-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/b3e2c70c13f0/JMP-34-149-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/2b6c2224dbdf/JMP-34-149-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/f71e5a04ff28/JMP-34-149-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/167b/2807680/62fce5c4e16e/JMP-34-149-g007.jpg

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本文引用的文献

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Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy.调强放射治疗优化乳腺癌治疗疗效
Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1336-44. doi: 10.1016/s0360-3016(02)03746-x.
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The impact of central lung distance, maximal heart distance, and radiation technique on the volumetric dose of the lung and heart for intact breast radiation.
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Whole Breast Irradiation with Halcyon™ 2.0: Workflow and Efficiency of Field-in-Field Treatment with Dynamic Beam Flattening Technique and kV Cone Beam Computed Tomography.使用Halcyon™ 2.0进行全乳照射:采用动态束流平坦化技术和千伏锥形束计算机断层扫描的野中野治疗工作流程与效率
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