Takumida M, Bagger-Sjöbäck D, Rask-Andersen H
Department of Otolaryngology, Karolinska Sjukhuset, Stockholm, Sweden.
ORL J Otorhinolaryngol Relat Spec. 1988;50(3):170-5. doi: 10.1159/000275986.
Carbonic anhydrase was detected histochemically in the guinea pig endolymphatic sac. The enzyme reaction was positive in both light and dark epithelial cells. In the former, the reaction product was found in the cytoplasm, especially around the intracytoplasmic vesicles and vacuoles. Reaction product was found in the basolateral infoldings as well. The dark epithelial cells also displayed carbonic anhydrase activity in the cytoplasm as well as in the lysosome-like bodies. It is suggested that this enzyme may be involved in (1) ionic or fluid regulation of the endolymph, (2) otoconia metabolism, and (3) phagocytotic activities.
用组织化学方法在豚鼠内淋巴囊检测到碳酸酐酶。在明细胞和暗细胞中酶反应均呈阳性。在明细胞中，反应产物见于细胞质，尤其是胞质内小泡和液泡周围。在基底外侧褶也发现有反应产物。暗细胞在细胞质以及类溶酶体小体中也显示碳酸酐酶活性。提示该酶可能参与（1）内淋巴的离子或液体调节，（2）耳石代谢，以及（3）吞噬活动。
