National Key Laboratory of Plant Molecular Genetics, CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, 200032, Shanghai, China.
Shanghai College of Life Science, University of Chinese Academy of Sciences, 200032, Shanghai, China.
Plant Cell Environ. 2019 Oct;42(10):2931-2944. doi: 10.1111/pce.13633. Epub 2019 Aug 13.
The ubiquitin-proteasome system (UPS) is a rapid regulatory mechanism for selective protein degradation in plants and plays crucial roles in growth and development. There is increasing evidence that the UPS is also an integral part of plant adaptation to environmental stress, such as drought, salinity, cold, nutrient deprivation and pathogens. This review focuses on recent studies illustrating the important functions of the UPS components E2s, E3s and subunits of the proteasome and describes the regulation of proteasome activity during plant responses to environment stimuli. The future research hotspots and the potential for utilization of the UPS to improve plant tolerance to stress are discussed.
泛素-蛋白酶体系统（UPS）是植物中一种快速的蛋白质选择性降解的调控机制，在生长和发育中起着至关重要的作用。越来越多的证据表明，UPS 也是植物适应环境胁迫（如干旱、盐度、寒冷、营养缺乏和病原体）的一个组成部分。本文综述了 UPS 组件 E2s、E3s 和蛋白酶体亚基的重要功能的最新研究，并描述了在植物对环境刺激的反应过程中蛋白酶体活性的调节。讨论了 UPS 未来的研究热点和利用 UPS 提高植物抗胁迫能力的潜力。
