Reynaud A E, Coude du Foresto B, Derriennic M, Courtieu A L
Laboratoire de Bactériologie A, Hôtel-Dieu, CHR, Nantes.
Pathol Biol (Paris). 1988 May;36(5):435-8.
The activity of 5 aminoglycosides compounds (habekacin, amikacin, gentamicin, netilmicin and tobramycin) was studied by an agar dilution method, against 235 strains of Enterobacteriaceae and 146 other Gram negative bacilli. 79 to 98% of susceptible strains were observed, according to the aminoglycoside compound. Habekacin and amikacin were the most effective, specially against the more frequently resistant bacteria: Enterobacter, Serratia, Hafnia, Acinetobacter, Pseudomonas aeruginosa. In comparison with a previous study, no evolution was observed in the resistance to aminoglycosides.
采用琼脂稀释法研究了5种氨基糖苷类化合物（哈贝卡星、阿米卡星、庆大霉素、奈替米星和妥布霉素）对235株肠杆菌科细菌和146株其他革兰氏阴性杆菌的活性。根据氨基糖苷类化合物的不同，观察到79%至98%的敏感菌株。哈贝卡星和阿米卡星最有效，尤其对更常见的耐药菌：肠杆菌属、沙雷菌属、哈夫尼菌属、不动杆菌属、铜绿假单胞菌。与之前的研究相比，未观察到对氨基糖苷类药物耐药性的变化。
