Westphal Thea, Konschake Wolfgang, Haase Hermann, Vollmer Marcus, Jünger Michael, Riebe Helene
Department of Dermatology, University of Greifswald, Greifswald, Germany.
Department of Bioinformatics, University of Greifswald, Greifswald, Germany.
Vasa. 2019 Nov;48(6):502-508. doi: 10.1024/0301-1526/a000812. Epub 2019 Jul 31.
Because of side effects like skin dryness and consecutive symptoms like itching the therapy of chronic venous insufficiency (CVI) with medical compression stockings (MCS) can lead to a diminished wear comfort and restricted compliance. Compression stockings with integrated skin care may have a positive influence on the skin hydration and moreover a positive effect on patients compliance. In this monocentric, randomized prospective, controlled trial a below knee conventional MCS was compared to a medical compression stocking with integrated skin care (MCS-SC), interface pressure range 23-32 mmHg. 50 patients with CVI. skin hydration. : transepidermal water loss, skin roughness, leg volume, interface pressure and questionnaires about quality of life and wear comfort. In patients wearing MCS the skin moisture decreased (p = 0.021) and the skin roughness increased significantly (p = 0.001), whereas in patients wearing the MCS-SC skin moisture and skin roughness changed only slightly (n.s.). These protective effects of MCS-SC compared to MCS were most common in patients with CVI at stage 3 (p = 0.046), in male patients (p = 0.013) and patients with initial dry skin (p = 0.034). Both MCS reduced lower leg volume, MCS by 80 ml (p < 0.001) and MCS-SC by 60 ml (p < 0.001), both MCS improved quality of life: leg complaints (p = 0.0003); functional status (p = 0.010), well-being and life satisfaction (p = 0.030). Wear comfort: In terms of tightness, constriction in bond area and strenuous donning the MCS-SC was assessed significantly more comfortable than MCS (p < 0.001). MCS-SC revealed to be superior to MCS with regard to skin moisture, particularly in patients with low skin humidity, in male patients and in patients with C3, varicose veins accompanied by edema.
由于诸如皮肤干燥等副作用以及瘙痒等连续症状，使用医用弹力袜（MCS）治疗慢性静脉功能不全（CVI）会导致穿着舒适度下降和依从性受限。具有皮肤护理功能的弹力袜可能对皮肤水合作用有积极影响，进而对患者的依从性产生积极作用。在这项单中心、随机前瞻性对照试验中，将一款膝下传统MCS与一款具有皮肤护理功能的医用弹力袜（MCS-SC）进行了比较，界面压力范围为23至32 mmHg。50例CVI患者。测量皮肤水合作用、经表皮水分流失、皮肤粗糙度、腿部体积、界面压力，并进行关于生活质量和穿着舒适度的问卷调查。穿着MCS的患者皮肤水分减少（p = 0.021），皮肤粗糙度显著增加（p = 0.001），而穿着MCS-SC的患者皮肤水分和皮肤粗糙度变化很小（无统计学意义）。与MCS相比，MCS-SC的这些保护作用在3期CVI患者中最为常见（p = 0.046），在男性患者中（p = 0.013）以及初始皮肤干燥的患者中（p = 0.034）。两种MCS均能减少小腿体积，MCS减少80 ml（p < 0.001），MCS-SC减少60 ml（p < 0.001），两种MCS均改善了生活质量：腿部不适（p = 0.0003）；功能状态（p = 0.010）、幸福感和生活满意度（p = 0.030）。穿着舒适度：在紧绷感、束带区域的压迫感和穿着费力程度方面，MCS-SC的舒适度评估明显高于MCS（p < 0.001）。在皮肤水分方面，MCS-SC显示优于MCS，尤其是在皮肤湿度低的患者、男性患者以及伴有水肿的C3期静脉曲张患者中。
