Mirakhmedova Sevara, Amirkhanov Amirkhan, Seliverstov Evgenii, Efremova Oksana, Zolotukhin Igor
Department of Surgery, Pirogov Russian National Research Medical University, Moscow 117997, Russia.
J Pers Med. 2023 Aug 27;13(9):1316. doi: 10.3390/jpm13091316.
There are no data on the daily regimen of compression therapy in patients with chronic venous disease. This systematic review aimed to establish the optimal daily duration of compression treatment. A systematic search of CENTRAL and MEDLINE was performed to identify RCTs, non-RCTs, reviews, systematic reviews, meta-analyses, and guidelines evaluating the use of compression regimens in the treatment of varicose veins. Thirty-two RCTs, three non-RCTs, four observational studies, and two crossover trials reporting the duration and regimes of compression treatment fulfilled the inclusion criteria. The daily duration of compression was reported in patients after invasive treatment, for venous ulcer treatment, in patients with venous symptoms. The quality of the studies varied. We could not conduct a meta-analysis due to the heterogeneity of the research data and their quality. Twenty-three studies reported results of compression usage after invasive procedures. Eight studies reported daily duration regimens in patients with venous ulcers. Nine studies reported the impact of compression on venous symptoms and/or edema or limb volume change. One study was conducted to assess if compression improves QoL in venous patients. While there was a clear difference found in the daily duration depending on the clinical scenario, no data in support of exact regimens were found. There are no reliable data supporting exact daily regimens of compression treatment in various cohorts of CVD patients.
关于慢性静脉疾病患者的压迫治疗日常方案，目前尚无相关数据。本系统评价旨在确定压迫治疗的最佳每日时长。对CENTRAL和MEDLINE进行了系统检索，以识别评估压迫方案在治疗静脉曲张中应用的随机对照试验（RCT）、非随机对照试验、综述、系统评价、荟萃分析和指南。32项随机对照试验、3项非随机对照试验、4项观察性研究以及2项报告压迫治疗时长和方案的交叉试验符合纳入标准。压迫治疗的每日时长在侵入性治疗后的患者、静脉溃疡治疗患者以及有静脉症状的患者中均有报告。研究质量各不相同。由于研究数据及其质量的异质性，我们无法进行荟萃分析。23项研究报告了侵入性手术后压迫治疗的结果。8项研究报告了静脉溃疡患者的每日时长方案。9项研究报告了压迫对静脉症状和/或水肿或肢体体积变化的影响。有1项研究评估了压迫是否能改善静脉疾病患者的生活质量（QoL）。虽然根据临床情况在每日时长上发现了明显差异，但未找到支持确切方案的数据。没有可靠数据支持不同队列的慢性静脉疾病（CVD）患者确切的压迫治疗日常方案。
