Ali Saqib, Farooq Imran
Department of Biomedical Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Protein Pept Lett. 2019;26(12):880-886. doi: 10.2174/0929866526666190731120018.
Amelognein protein plays a vital role in the formation and mineralization of enamel matrix. Amelogenin structure is complex in nature and researchers have studied it with different experimental techniques. Considering its important role, there is a need to understand this important protein, which has been discussed in detail in this review. In addition, various experimental techniques to study amelogenin protein used previously have been tackled along with their advantages and disadvantages. A selection of 67 relevant articles/book chapters was included in this study. The review concluded that amelogenins act as nanospheres or spacers for the growth of enamel crystals. Various experimental techniques can be used to study amelogenins, however, their advantages and drawbacks should be kept in mind before performing analysis.
釉原蛋白在釉质基质的形成和矿化过程中起着至关重要的作用。釉原蛋白的结构本质上很复杂，研究人员已采用不同的实验技术对其进行研究。鉴于其重要作用，有必要了解这种重要的蛋白质，本综述对此进行了详细讨论。此外，还探讨了先前用于研究釉原蛋白的各种实验技术及其优缺点。本研究纳入了67篇相关文章/书籍章节。该综述得出结论，釉原蛋白作为釉质晶体生长的纳米球或间隔物。可以使用各种实验技术来研究釉原蛋白，然而，在进行分析之前应牢记它们的优缺点。
