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埃塞俄比亚西北部选定暴发地区口蹄疫的传播动态。

Transmission dynamics of foot and mouth disease in selected outbreak areas of northwest Ethiopia.

机构信息

University of Gondar, College of Veterinary Medicine and Animal Sciences,Department of Veterinary Epidemiology and Public Health,P.O. Box. 196, Gondar,Ethiopia.

出版信息

Epidemiol Infect. 2019 Jan;147:e189. doi: 10.1017/S0950268819000803.

Abstract

Foot and mouth disease (FMD) is a highly contagious and economically important disease of cloven-hoofed animals, which is endemic in Ethiopia. An outbreak follow-up study was undertaken to quantify the transmission parameters of FMD in the crop-livestock mixed (CLM) system and commercial dairy farms in selected areas of northwest Ethiopia. The transmission parameters were quantified using a generalised linear model (GLM) based on a susceptible-infectious-recovered (SIR) epidemic model. The per day average transmission rate between animals was 0.26 (95% CI 0.22-0.32) and 0.33 (95% CI 0.21-0.57) in the CLM system and in the commercial dairy farms, respectively. The average basic reproduction ratio of FMD was 1.68 (95% CI 1.42-2.07) in the CLM system and 1.98 (95% CI 1.26-3.42) in the commercial dairy farms. The medium per day transmission rate and moderate basic reproduction ratio observed in this study indicated that a vaccination coverage needed to stop transmission of the disease in these populations might not be very high.

摘要

口蹄疫(FMD)是一种高度传染性且经济上非常重要的偶蹄动物疾病,在埃塞俄比亚流行。本研究开展了一次暴发后随访研究,以量化作物-牲畜混合(CLM)系统和选定的埃塞俄比亚西北部商业奶牛场中 FMD 的传播参数。使用基于易感-感染-恢复(SIR)流行模型的广义线性模型(GLM)量化了传播参数。CLM 系统和商业奶牛场中动物之间的日平均传播率分别为 0.26(95%CI 0.22-0.32)和 0.33(95%CI 0.21-0.57)。FMD 的平均基本繁殖率在 CLM 系统和商业奶牛场中分别为 1.68(95%CI 1.42-2.07)和 1.98(95%CI 1.26-3.42)。本研究中观察到的中等日平均传播率和中等基本繁殖率表明,要在这些人群中停止疾病传播,所需的疫苗接种覆盖率可能不会很高。

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