Guangzhou Centre for Diseases Control and Prevention,Guangzhou,China.
Epidemiol Infect. 2019 Jan;147:e207. doi: 10.1017/S0950268819000992.
To compare the epidemiologic features (e.g. settings and transmission mode) and patient clinical characteristics associated with outbreaks of different norovirus (Nov) strains, we retrospectively analysed data of Nov outbreaks occurring in Guangzhou, China from 2012 to 2018. The results suggested that outbreaks of Nov GII.2, GII.17 and GII.4 Sydney exhibited different outbreak settings, transmission modes and symptoms. GII.2 outbreaks mainly occurred in kindergartens, elementary and high schools and were transmitted mainly through person-to-person contact. By contrast, GII.4 Sydney outbreaks frequently occurred in colleges and were primarily associated with foodborne transmission. Cases from GII.2 and GII.17 outbreaks reported vomiting more frequently than those from outbreaks associated with GII.4 Sydney.
为了比较不同诺如病毒（Nov）株引起的暴发在流行病学特征（如地点和传播模式）和患者临床特征方面的差异，我们回顾性分析了 2012 年至 2018 年期间中国广州发生的诺如病毒暴发的数据。结果表明，诺如病毒 GII.2、GII.17 和 GII.4 Sydney 暴发具有不同的暴发地点、传播模式和症状。GII.2 暴发主要发生在幼儿园、小学和中学，主要通过人与人接触传播。相比之下，GII.4 Sydney 暴发常发生在大学，主要与食源性传播有关。GII.2 和 GII.17 暴发的病例比 GII.4 Sydney 暴发的病例更常报告呕吐。
