贝利尤单抗成功治疗系统性红斑狼疮性胸膜心包炎。
Successful treatment of systemic lupus erythematosus pleuropericarditis with belimumab.
作者信息
Carrión-Barberà Irene, Salman-Monte Tarek Carlos, Castell Sonia, Castro-Domínguez Francisco, Ojeda Fabiola, Monfort Jordi
机构信息
Department of Rheumatology, Hospital del Mar, Barcelona, Spain.
出版信息
Eur J Rheumatol. 2019 May 20;6(3):150-152. doi: 10.5152/eurjrheum.2019.17169. Print 2019 Jul.
Abstract
Systemic lupus erythematosus (SLE) is characterized by a wide variety of manifestations and a difficult disease control in some patients. We present the case of a 51-year-old woman who presented with a flare of SLE including arthritis and pleuropericarditis that responded to neither leflunomide, methotrexate, nor high doses of prednisone. After initiating treatment with belimumab, the patient experienced a quick and notorious improvement. She remains stable to this day while continuing belimumab therapy.
摘要
系统性红斑狼疮（SLE）的特点是表现形式多种多样，且部分患者的病情难以控制。我们报告一例51岁女性患者，其SLE病情发作，伴有关节炎和胸膜心包炎，来氟米特、甲氨蝶呤及大剂量泼尼松治疗均无效。使用贝利尤单抗治疗后，患者病情迅速且显著改善。至今继续使用贝利尤单抗治疗，病情保持稳定。
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