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儿童原发性皮肤淋巴瘤:4例报告

Primary cutaneous lymphoma in children: A report of four cases.

作者信息

Chen Faling, Liu Jiangbin, Lv Zhibao, Huang Yimin, Wu Yibo

机构信息

Department of General Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.

出版信息

Turk J Pediatr. 2018;60(6):739-743. doi: 10.24953/turkjped.2018.06.017.

DOI:10.24953/turkjped.2018.06.017
PMID:31365213
Abstract

Chen F, Liu J, Lv Z, Huang Y, Wu Y. Primary cutaneous lymphoma in children: A report of four cases. Turk J Pediatr 2018; 60: 739-743. Primary cutaneous lymphoma (CL) is a malignant lymphoma presenting in the skin. Primary CL is rare in children and difficult to clinically diagnose. We report four pediatric cases of primary CL with tumors in different body area: case 1, on the face and left thigh; case 2, on the left side of the neck; case 3, on the left side of the back; and case 4, on the left buttock. The first diagnoses of these children were rash, abscess, lymphadenitis, and fever, respectively in local hospitals. All 4 patients were diagnosed as primary CL by histopathologic examination in our hospital. Three patients (case 1, case 2 and case 4) were treated with chemotherapy. The size of tumor and degree of cutaneous lesion were alleviated after chemotherapy. Case 3 refused to receive chemotherapy, and died. The cases indicated the importance of early diagnosis of primary CL to guide appropriate therapy.

摘要

陈F、刘J、吕Z、黄Y、吴Y。儿童原发性皮肤淋巴瘤:4例报告。《土耳其儿科学杂志》2018年;60:739 - 743。原发性皮肤淋巴瘤(CL)是一种发生于皮肤的恶性淋巴瘤。原发性CL在儿童中罕见,临床诊断困难。我们报告4例儿童原发性CL,肿瘤位于不同身体部位:病例1,位于面部和左大腿;病例2,位于颈部左侧;病例3,位于背部左侧;病例4,位于左臀部。这些儿童最初在当地医院分别被诊断为皮疹、脓肿、淋巴结炎和发热。所有4例患者在我院经组织病理学检查均被诊断为原发性CL。3例患者(病例1、病例2和病例4)接受了化疗。化疗后肿瘤大小和皮肤病变程度有所减轻。病例3拒绝接受化疗,死亡。这些病例表明原发性CL早期诊断对于指导恰当治疗的重要性。

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