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[兔滑液pH值的实验性改变。气体分析研究]

[Experimental modification of the pH value of the synovial fluid of rabbits. Gas analysis studies].

作者信息

Trzenschik K

机构信息

Poliklinik für Orthopädie des Bereichs Medizin (Charitè) der Humboldt-Universität zu Berlin.

出版信息

Z Orthop Ihre Grenzgeb. 1988 Mar-Apr;126(2):200-4. doi: 10.1055/s-2008-1044893.

DOI:10.1055/s-2008-1044893
PMID:3136604
Abstract

After the intraarticular injection of isoosmolalic acid (pH 5.0) or alkaline (pH 10.0) buffer solutions into the right knee joints and physiological buffer solution (pH 7.3) into the left side (control) of rabbits are aspirated samples of synovial fluid during a period of 90-120 minutes. The pH value, carbondioxid tension (pCO2) and oxygen tension (pO2) are determinated with an Astrup-equipment. The injection of an acid or alkaline buffer solution is followed immediately by a decrease or increase of the pH value. During a period of 60-70 minutes is continuously reached the physiological pH level. The repeated injections of an acid buffer solution don't cause an adaptation effect to the pH 'overloading'. The pH value and pCO2 have a reciprocal relationship.

摘要

向兔右膝关节内注射等渗酸溶液(pH 5.0)或碱性缓冲溶液(pH 10.0),并向左侧膝关节(对照)注射生理缓冲溶液(pH 7.3),在90 - 120分钟内抽取关节液样本。使用阿斯特鲁普设备测定pH值、二氧化碳分压(pCO2)和氧分压(pO2)。注射酸性或碱性缓冲溶液后,pH值会立即下降或上升。在60 - 70分钟内会持续达到生理pH水平。重复注射酸性缓冲溶液不会对pH“过载”产生适应效应。pH值和pCO2呈反比关系。

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