Fujimura T, Yonemura Y, Urade M, Sugiyama K, Hasegawa H, Hashimoto T, Miyata R, Matsuda Y, Katayama K, Yamaguchi A
2nd Dep. of Surgery, School of Medicine, Kanazawa University.
Gan To Kagaku Ryoho. 1988 Aug;15(8):2331-4.
A 58-year-old woman who had undergone subtotal gastrectomy for advanced gastric cancer yielded massive ascites after 6 months. The cytology of ascites showing Class V indicated recurrence of peritoneal dissemination in the gastric cancer. Since laparotomy disclosed diffusely small tubercular seedings in all areas of the peritoneal cavity, she received continuous hyperthermic peritoneal perfusion (CHPP) with 300 mg Cisplatin and 30 mg Mitomycin C. After CHPP ascites disappeared for 4 months. Macroscopically and microscopically, there was no cancerous lesion in the peritoneal cavity by following second-look operation. This result encouraged us to try therapeutic CHPP for overt peritoneal dissemination.
一名58岁女性因晚期胃癌接受了胃大部切除术，6个月后出现大量腹水。腹水细胞学检查显示为V级，提示胃癌腹膜播散复发。由于剖腹手术发现腹膜腔所有区域均有弥漫性小结节状播散灶，她接受了含300毫克顺铂和30毫克丝裂霉素C的持续热灌注化疗（CHPP）。CHPP后腹水消失了4个月。二次探查手术显示，腹膜腔在宏观和微观上均无癌性病变。这一结果促使我们尝试对明显的腹膜播散进行治疗性CHPP。
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