在社区实践环境中，细胞学涂片可提高卵巢肿瘤冰冻切片的准确性。
Cytologic smears improve accuracy of frozen sections of ovarian tumors in the community practice settings.
作者信息
Cimic Adela, Mironova Maria, Khoury-Collado Fady, Salih Ziyan
机构信息
Address: Department of Pathology, Maimonides Medical Center, Brooklyn, NY, USA.
Maimonides Medical Center, Brooklyn, NY, USA.
出版信息
Cytojournal. 2019 May 24;16:10. doi: 10.4103/cytojournal.cytojournal_20_18. eCollection 2019.
BACKGROUND
The ovaries can be the site for various primary tumors and also the presenting site of metastatic disease. Quick and correct intraoperative diagnosis is crucial for the patient's further management. The aim of this study was to demonstrate the advantages of the combined diagnostic method - ovarian frozen sections in conjunction with cytologic smears.
METHODS
From June 2016 to June 2017, we prospectively prepared additional two cytologic smears with Diff-Quik stain on ovarian frozen sections comprised of two hematoxylin and eosin sections. For quality assurance purposes, we compared the results of frozen section discrepancies and deferrals with those that of the previous year from June 2015 to June 2016.
RESULTS
With the introduction of cytologic smears to ovarian frozen sections, the number of discrepancies and deferrals combined decreased from 13.75% to 7.85%. The most benefit of smears was observed in primary ovarian malignancies.
CONCLUSIONS
In the setting where all the members of the pathology group render cytologic evaluations routinely, smears play an important complementary role.
背景
卵巢可能是各种原发性肿瘤的发生部位，也是转移性疾病的首发部位。快速准确的术中诊断对患者的进一步治疗至关重要。本研究的目的是证明联合诊断方法——卵巢冰冻切片联合细胞学涂片的优势。
方法
2016年6月至2017年6月，我们前瞻性地在由两张苏木精和伊红切片组成的卵巢冰冻切片上额外制备了两张用Diff-Quik染色的细胞学涂片。为保证质量，我们将冰冻切片差异和延迟诊断的结果与2015年6月至2016年6月前一年的结果进行了比较。
结果
随着细胞学涂片应用于卵巢冰冻切片，差异和延迟诊断的总数从13.75%降至7.85%。涂片在原发性卵巢恶性肿瘤中显示出最大益处。
结论
在病理团队所有成员都常规进行细胞学评估的情况下，涂片发挥着重要的辅助作用。
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