Mika Okura, Kyoto University, Kyoto, Kyoto Japan,
J Nutr Health Aging. 2019;23(7):654-664. doi: 10.1007/s12603-019-1217-7.
The present study examined whether the combination of self-reported mobility decline (SR-MD) and cognitive decline (SR-CD) was associated with mortality and new long-term care insurance (LTCI) service certifications based on sex and age.
A prospective cohort study.
We analyzed cohort data from a sample of older adult residents in Kami Town, Japan. The response rate was 94.3%, and we followed 5,094 older adults for 3 years. Full analyses were conducted on 5,076 participants.
A total of four groups were determined through self-reported responses on the Kihon Checklist for SR-MD (a score of 3 or more on 5 items) and SR-CD (a score of 1 or more on 3 items): non-SR-cognitive frailty, non-SR-MD and SR-CD, SR-MD and non-SR-CD, and SR-cognitive frailty.
Main outcomes included mortality (n = 262) or new certifications for LTCI services (n = 708) during the 3-year period. Excluding overlapping, this included 845 older adults (16.6%). Among men, prevalence of non-SR-cognitive frailty, non-SR-MD and SR-CD, SR-MD and non-SR-CD, and SR-cognitive frailty (SR-MD and SR-CD) was 48.2%, 26.4%, 11.5%, and 13.8%, respectively. Respective rates for women were 45.7%, 15.5%, 23.1%, and 15.7%. Multivariate analyses revealed that for men, SR-MD and non-SR-CD significantly affected adverse health outcomes, leading to earlier negative outcomes relative to the non-SR-MD and SR-CD group. For women, non-SR-MD and SR-CD and SR-MD and non-SR-CD had similar slopes.
The impact of SR-MD or SR-CD on adverse health outcomes differed as a function of age and sex. Thus, we need to consider preventive approaches according to these specific target group features.
本研究旨在探讨基于性别和年龄,自我报告的活动能力下降(SR-MD)和认知能力下降(SR-CD)的组合是否与死亡率和新的长期护理保险(LTCI)服务认证相关。
前瞻性队列研究。
我们分析了来自日本上之乡镇老年居民样本的队列数据。回复率为 94.3%,我们对 5094 名老年人进行了 3 年的随访。对 5076 名参与者进行了全面分析。
通过自我报告的 Kihon Checklist 回答确定了以下四个组别:非 SR-认知脆弱性、非 SR-MD 和 SR-CD、SR-MD 和非 SR-CD、以及 SR-认知脆弱性。
主要结局包括 3 年内的死亡率(n=262)或 LTCI 服务的新认证(n=708)。排除重叠项后,这包括 845 名老年人(16.6%)。在男性中,非 SR-认知脆弱性、非 SR-MD 和 SR-CD、SR-MD 和非 SR-CD、以及 SR-认知脆弱性(SR-MD 和 SR-CD)的患病率分别为 48.2%、26.4%、11.5%和 13.8%。女性相应的患病率分别为 45.7%、15.5%、23.1%和 15.7%。多变量分析显示,对于男性,SR-MD 和非 SR-CD 显著影响不良健康结局,导致相对于非 SR-MD 和 SR-CD 组更早出现负面结局。对于女性,非 SR-MD 和 SR-CD 以及 SR-MD 和非 SR-CD 具有相似的斜率。
SR-MD 或 SR-CD 对不良健康结局的影响因年龄和性别而异。因此,我们需要根据这些特定的目标群体特征考虑预防措施。