Department of Radiotherapy Quality Management, Yokohama CyberKnife Center, 574-1, Ichisawa-cho, Asahi-ku, Yokohama, 241-0014, Japan.
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Jpn J Radiol. 2019 Oct;37(10):727-734. doi: 10.1007/s11604-019-00859-7. Epub 2019 Jul 31.
To analyze the factors affecting the tracking accuracy of the CyberKnife Synchrony Respiratory Tracking System (SRTS).
A dynamic motion phantom (motion phantom) reproduced the respiratory motions of each patient treated with the SRTS using a ball as the target. CyberKnife tracked the ball using the SRTS, and this process was recorded by a video camera mounted on the linear accelerator head. The tracking error was evaluated from the images captured by the video camera. Multiple regression analysis was used to identify factors affecting tracking accuracy from 91 cases.
The median tracking error was 1.9 mm (range 0.9-5.3 mm). Four factors affected the tracking accuracy: the average absolute amplitude of the tumor motion in the cranio-caudal (CC) direction (p = 0.007), average position gap due to the phase shift between the internal tumor and external marker positions in the CC direction (p < 0.001), and average velocity of the tumor in the CC (p < 0.001) and anterior-posterior directions (p = 0.033).
We identified factors that affected tracking accuracy. This information may assist the identification of suitable margins that should be added to each patient's clinical target volume.
分析影响 CyberKnife Synchrony 呼吸追踪系统(SRTS)追踪精度的因素。
采用一个动态运动体模(运动体模),以球体作为目标,模拟每位接受 SRTS 治疗的患者的呼吸运动。CyberKnife 使用 SRTS 追踪球体,该过程由安装在直线加速器头部的摄像机记录。从摄像机拍摄的图像中评估追踪误差。对 91 例患者进行多元回归分析,以确定影响追踪精度的因素。
中位追踪误差为 1.9 毫米(范围 0.9-5.3 毫米)。有四个因素影响了追踪精度:肿瘤在头脚方向(CC)的平均绝对运动幅度(p=0.007)、由于肿瘤内部位置和外部标记位置在 CC 方向的相位差导致的平均位置差距(p<0.001),以及肿瘤在 CC 方向(p<0.001)和前后方向(p=0.033)的平均速度。
我们确定了影响追踪精度的因素。这些信息可能有助于确定每个患者临床靶体积应增加的合适边界。