Limketkai Berkeley N, Shah Neha D, Sheikh Ghias N, Allen Karen
Vatche and Tamar Manoukian Division of Digestive Diseases, UCLA School of Medicine, 100 Medical Center Drive, Suite 345, Los Angeles, CA, 90095, USA.
Comprehensive Cancer Center, Stanford Health Care, Palo Alto, CA, USA.
Curr Gastroenterol Rep. 2019 Jul 31;21(9):47. doi: 10.1007/s11894-019-0708-3.
To discuss the different forms of enteral nutrition, while outlining available evidence for its use in specific conditions and how enteral nutrition composition may or may not influence relevant outcomes.
Enteral nutrition formulas were originally conceived as a liquid form of nutrition for individuals who otherwise could not consume adequate calories through solid food. Over time, the emergence of specialty formulas marketed to benefit specific diseases or conditions has led to a broad range of potentially confusing options. While most options have theoretical benefit for their marketed conditions, the evidence demonstrating practical benefit is not consistent. Overall, the certainty of evidence for specialty formulas remains low or very low. In most instances, one could begin with standard polymeric formula, except in cases where disease-specific formulas are recommended. Much research is nonetheless still needed to clarify whether some disease-specific formulas are truly beneficial or merely theoretical features.
讨论肠内营养的不同形式,概述其在特定情况下使用的现有证据,以及肠内营养成分如何可能影响或不影响相关结果。
肠内营养配方最初是为那些无法通过固体食物摄入足够热量的个体设计的液体营养形式。随着时间的推移,针对特定疾病或状况销售的特殊配方的出现导致了一系列可能令人困惑的选择。虽然大多数选择对其销售的状况具有理论上的益处,但证明实际益处的证据并不一致。总体而言,特殊配方的证据确定性仍然很低或非常低。在大多数情况下,可以从标准的聚合物配方开始,除非推荐使用特定疾病的配方。然而,仍需要大量研究来阐明某些特定疾病的配方是否真的有益,还是仅仅具有理论特征。