酶进化实验。铜绿假单胞菌酰胺酶的研究。
An experiment in enzyme evolution. Studies with Pseudomonas aeruginosa amidase.
作者信息
Clarke P H, Drew R
机构信息
Department of Biochemistry, University College London, UK.
出版信息
Biosci Rep. 1988 Apr;8(2):103-20. doi: 10.1007/BF01116455.
PMID:3136812
Abstract
The regulation of amidase synthesis in P. aeruginosa is under positive control. This review describes the experimental evolution of amidase and its regulator protein for the hydrolysis of novel substrates and experiments to elucidate the mechanism of the control system.
摘要
铜绿假单胞菌中酰胺酶合成的调控受正向控制。本综述描述了酰胺酶及其调节蛋白针对新型底物水解的实验进化过程，以及阐明控制系统机制的实验。
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