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老年髋部骨折患者早期握力评估能否预测功能结局?

Can early assessment of hand grip strength in older hip fracture patients predict functional outcome?

机构信息

Clinic for Physical Medicine and Rehabilitation, Clinical Center of Serbia, Belgrade, Serbia.

Faculty of Medicine, University of Belgrade, Belgrade, Serbia.

出版信息

PLoS One. 2019 Aug 1;14(8):e0213223. doi: 10.1371/journal.pone.0213223. eCollection 2019.

Abstract

Decreased muscle strength is not only a risk factor for hip fracture in older patients, but plays a role in recovery of physical function. Our aim was to assess the role of grip strength measured early after hip fracture, and classified according to the EWGSOP2 criteria in predicting short- and long-term functional recovery. One hundred ninety-one patients with acute hip fracture consecutively admitted to an orthopaedic hospital have been selected. A multidimensional geriatric assessment evaluating sociodemographic variables, cognitive status, functional status and quality of life prior to fracture, as well as perioperative variables were performed. Follow-ups at 3 and 6 months after surgery were carried out to evaluate functional recovery. Multivariate regression models were used to assess the predictive role of handgrip strength. The mean age of the participants was 80.3 ±6.8 years. Thirty-five percent of our patients with clinically relevant hand grip strength weakness were significantly older, more often female, had a lower BMI, and were of worse physical health. They also had a lower cognitive level, lower Barthel index, and lower EQ5D scores before fracture. Multivariate regression analysis adjusted for age and gender revealed that hand grip weakness was an independent predictor of worse functional outcome at 3 and 6 months after hip fracture for both genders and in all age populations. Our study supports the prognostic role of hand grip strength assessed at hospital admission in patients with hip fracture. Thus, clinicians should be encouraged to include hand grip assessment in their evaluation of hip fracture patients in the acute setting in order to optimize treatment of high-risk individuals.

摘要

肌肉力量下降不仅是老年患者髋部骨折的危险因素,而且在身体功能恢复中起作用。我们的目的是评估髋部骨折后早期测量的握力在预测短期和长期功能恢复中的作用,并根据 EWGSOP2 标准进行分类。我们选择了 191 例连续入住骨科医院的急性髋部骨折患者。进行了多维老年评估,评估了骨折前的社会人口统计学变量、认知状态、功能状态和生活质量,以及围手术期变量。术后 3 个月和 6 个月进行随访,以评估功能恢复情况。使用多元回归模型评估握力的预测作用。参与者的平均年龄为 80.3±6.8 岁。我们有 35%的临床相关握力弱的患者明显年龄更大、更多为女性、BMI 更低、身体健康状况更差。他们在骨折前的认知水平、Barthel 指数和 EQ5D 评分也更低。调整年龄和性别后的多元回归分析显示,握力弱是髋部骨折后 3 个月和 6 个月时男女两性和所有年龄组患者功能结局较差的独立预测因素。我们的研究支持在髋部骨折患者入院时评估握力的预后作用。因此,临床医生应该鼓励在急性环境中评估髋部骨折患者时包括握力评估,以便为高风险个体优化治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74f4/6675283/aae6d6ba9f90/pone.0213223.g001.jpg

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