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Rebound-associated vertebral fractures after stopping denosumab: Report of four cases.

作者信息

Dupont Jolan, Laurent Michaël R, Dedeyne Lenore, Luyten Frank P, Gielen Evelien, Dejaeger Marian

机构信息

Gerontology & Geriatrics, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Herestraat 49 box 7003, 3000 Leuven, Belgium; Department of Geriatric Medicine, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.

Gerontology & Geriatrics, Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), KU Leuven, Herestraat 49 box 7003, 3000 Leuven, Belgium; Centre for Metabolic Bone Diseases, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium; Imelda Hospital, Imeldalaan 9, 2820 Bonheiden, Belgium.

出版信息

Joint Bone Spine. 2020 Mar;87(2):171-173. doi: 10.1016/j.jbspin.2019.07.010. Epub 2019 Jul 29.

DOI:10.1016/j.jbspin.2019.07.010
PMID:31369866
Abstract
摘要

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No overshoot of bone turnover after withdrawal of denosumab treatment of adults with Langerhans cell histiocytosis: a prospective clinical trial.成人朗格汉斯细胞组织细胞增多症患者停用地诺单抗治疗后骨转换无过度现象:一项前瞻性临床试验
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Similarities and Differences in the Management of Patients with Osteoporotic Vertebral Fractures and Those with Rebound-Associated Vertebral Fractures Following Discontinuation of Denosumab.骨质疏松性椎体骨折患者与停用地诺单抗后出现反弹相关椎体骨折患者的管理异同
J Clin Med. 2023 Sep 10;12(18):5874. doi: 10.3390/jcm12185874.
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Is Adynamic Bone Always a Disease? Lessons from Patients with Chronic Kidney Disease.骨动力不足就一定是疾病吗?来自慢性肾病患者的经验教训。
J Clin Med. 2022 Nov 30;11(23):7130. doi: 10.3390/jcm11237130.
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Long-term follow up after denosumab treatment for osteoporosis - rebound associated with hypercalcemia, parathyroid hyperplasia, severe bone mineral density loss, and multiple fractures: a case report.地诺单抗治疗骨质疏松症后的长期随访——与高钙血症、甲状旁腺增生、严重骨密度丧失及多处骨折相关的反弹:一例报告
J Med Case Rep. 2020 Aug 11;14(1):130. doi: 10.1186/s13256-020-02401-0.