Balaeva Tatiana, Grjibovski Andrej M, Samodova Olga, Sannikov Anatoly, Klouman Elise
a Department of Community Medicine, UiT The Arctic University of Norway , Tromsø , Norway.
b Department of Public Health, Northern State Medical University , Arkhangelsk , Russia.
Int J Circumpolar Health. 2019 Dec;78(1):1648970. doi: 10.1080/22423982.2019.1648970.
Hepatitis C, caused by the hepatitis C virus (HCV), is a major public health issue in Russia. The aim of our study was to assess the seroprevalence of markers of HCV exposure and factors associated with HCV seropositivity among the general population aged 18-39 years in the city of Arkhangelsk, Northwest Russia. A social research agency applied a quota sampling method to recruit study participants using cell phone numbers. All participants (n = 1243) completed a self-administered questionnaire and provided a blood sample. Sixty-five participants (5.2%, 95% confidence interval [CI] 4.9-5.5) tested positive for HCV IgM+G antibodies, and of these, 55 (84.6%) did not know that they were exposed to HCV. In multivariable logistic regression analysis, HCV seropositivity was significantly associated with older age, a history of injecting drug use, and having ever received a blood transfusion. To reach the goal of the World Health Organisation's Global Health Sector Strategy on Viral Hepatitis, regional preventive programmes should include measures to reduce injecting drug use as well as scaling up harm-reduction and treatment programs for drug addicts.
丙型肝炎由丙型肝炎病毒（HCV）引起，是俄罗斯的一个重大公共卫生问题。我们研究的目的是评估俄罗斯西北部阿尔汉格尔斯克市18至39岁普通人群中HCV暴露标志物的血清流行率以及与HCV血清阳性相关的因素。一家社会研究机构采用配额抽样方法，通过手机号码招募研究参与者。所有参与者（n = 1243）完成了一份自填式问卷并提供了血样。65名参与者（5.2%，95%置信区间[CI] 4.9 - 5.5）HCV IgM + G抗体检测呈阳性，其中55名（84.6%）不知道自己接触过HCV。在多变量逻辑回归分析中，HCV血清阳性与年龄较大、注射吸毒史以及曾接受输血显著相关。为实现世界卫生组织病毒性肝炎全球卫生部门战略的目标，区域预防计划应包括减少注射吸毒的措施，以及扩大针对吸毒者的减少伤害和治疗计划。
