Oper Dent. 2019 Nov/Dec;44(6):E271-E278. doi: 10.2341/18-278-L. Epub 2019 Aug 2.
The aim of this study was to investigate the biofilm formation and cell viability of a polymer-infiltrated ceramic (PIC) and an yttria-stabilized polycrystalline zirconium dioxide ceramic (Y-TZP). The null hypothesis was that there would be no difference in biofilm formation and cell viability between the materials.
biofilm was analyzed with scanning electron microscopy (SEM), confocal laser scanning microscopy, and colony counting (colony-forming units/mL). The cell viability (fibroblasts) of both materials was measured with 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium) (MTT) test. Roughness measurements were also performed.
The PIC displayed higher roughness but showed similar colony-forming units and biovolume values to those of Y-TZP. SEM showed a higher amount of adhered fibroblasts on the PIC surface on the first day and similar amounts on both materials after seven days. Moreover, the materials were biocompatible with human fibroblasts.
PIC and Y-TZP are biocompatible and present the same characteristics for biofilm formation; therefore, they are indicated for indirect restorations and implant abutments.
本研究旨在探讨聚合物渗透陶瓷（PIC）和氧化钇稳定四方氧化锆陶瓷（Y-TZP）的生物膜形成和细胞活力。假设这两种材料的生物膜形成和细胞活力没有差异。
用扫描电子显微镜（SEM）、共聚焦激光扫描显微镜和菌落计数（菌落形成单位/mL）分析生物膜。用 3-（4,5-二甲基噻唑-2-基）-2,5-二苯基四氮唑（MTT）试验测量两种材料的细胞活力（成纤维细胞）。还进行了粗糙度测量。
PIC 显示出更高的粗糙度，但与 Y-TZP 的菌落形成单位和生物体积值相似。SEM 显示，在第一天，PIC 表面附着的成纤维细胞数量更多，而在第 7 天，两种材料的附着细胞数量相似。此外，这些材料与人成纤维细胞具有生物相容性。
PIC 和 Y-TZP 具有生物相容性，并且具有相同的生物膜形成特性；因此，它们适用于间接修复体和种植体基台。
