Cui Xin, Liang Long, Wei Xu, Liao Xing, Li Yongyao, Cheng Hao, Xie Yanming, Cheng Yongzhong, Du Yachao, Liu Guangwei, Zhang Hongyan, Wang Shiheng, Liu Jiani, Wang Zhibo, Zhang Yue, Tian Yaliang
Wangjing Hospital.
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing.
Medicine (Baltimore). 2019 Aug;98(31):e16562. doi: 10.1097/MD.0000000000016562.
Distal radius fractures (DRFs) is one of the most common bone injuries in children, which may lead to deformity and other complications if the treatment is not prompt or appropriate. Splints external fixation is a common conservative treatment for such fractures. Therefore, we conducted a systematic review and meta-analysis to explore the efficacy, safety and cost benefits of splints in the treatment of DRFs in children.
PubMed, Web of Science, Embase, Cochrane Library, Cochrane Central Register of Controlled Trials (CENTRAL), and ClinicalTrials.gov, Chinese National Knowledge Infrastructure Database (CNKI), Wanfang Database, and VIP Database were searched for eligible randomized controlled trials (RCTs). The methodological quality of the included studies and the level of evidence for results were assessed, respectively, using the risk bias assessment tool of Cochrane and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method. Statistical analysis was conducted with Revman 5.3.
This study will analyze and integrate the existing evidence for effectiveness, safety and cost benefits of splints on DRFs in children.
The conclusion of this study will provide evidence to effectiveness, safety and cost benefits of splints on DRFs in children, which can further guide the selection of appropriate interventions.
CRD42019123429.
桡骨远端骨折（DRFs）是儿童最常见的骨损伤之一，如果治疗不及时或不恰当，可能会导致畸形和其他并发症。夹板外固定是此类骨折常见的保守治疗方法。因此，我们进行了一项系统评价和荟萃分析，以探讨夹板治疗儿童DRFs的疗效、安全性和成本效益。
检索了PubMed、Web of Science、Embase、Cochrane图书馆、Cochrane对照试验中央注册库（CENTRAL）和ClinicalTrials.gov、中国国家知识基础设施数据库（CNKI）、万方数据库和维普数据库，以查找符合条件的随机对照试验（RCT）。分别使用Cochrane的风险偏倚评估工具和推荐分级评估、制定与评价（GRADE）方法评估纳入研究的方法学质量和结果的证据水平。使用Revman 5.3进行统计分析。
本研究将分析和整合现有关于夹板治疗儿童DRFs有效性、安全性和成本效益的证据。
本研究的结论将为夹板治疗儿童DRFs的有效性、安全性和成本效益提供证据，可进一步指导适当干预措施的选择。
PROSPERO注册号：CRD42019123429。
