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在初次全膝关节置换术中,收肌管阻滞与局部浸润镇痛的比较:一项随机对照试验的荟萃分析。

Comparison of adductor canal block with local infiltration analgesia in primary total knee arthroplasty: A meta-analysis of randomized controlled trials.

机构信息

Department of Orthopedics, The First People's Hospital of Changzhou, 185 Juqian Road, Changzhou, 213003, Jiangsu, China.

Department of Orthopedics, The First People's Hospital of Changzhou, 185 Juqian Road, Changzhou, 213003, Jiangsu, China.

出版信息

Int J Surg. 2019 Sep;69:89-97. doi: 10.1016/j.ijsu.2019.07.024. Epub 2019 Jul 30.

Abstract

BACKGROUND

Currently, there remains a paucity of literature about the efficiency of adductor canal block (ACB) versus local infiltration analgesia (LIA) for pain management after total knee arthroplasty (TKA). The purpose of this study was to perform a relatively credible and overall assessment to compare the efficiency of ACB versus LIA for early postoperative pain treatment after TKA.

METHODS

A comprehensive search of the published literature in PubMed, MEDLINE, Cochrane, EMBASE, and Web of Science databases was performed. Only randomized clinical trials (RCTs) or quasi-RCTs were included in this study. The primary outcome was pain score. Secondary outcome measures included opioid consumption, functional outcome (such as timed up and go test and distance walked), and length of stay.

RESULTS

Eight RCTs with a total of 675 patients were included. No statistically significant difference was observed between the ACB and LIA groups in pain scores at 24 h or 48 h, total opioid consumption at 24 h or 48 h, and length of stay. However, the LIA group exhibited greater improvements in ambulation ability (P = 0.03) and distance walked (P < 0.00001).

CONCLUSIONS

Both treatments provide similar overall pain relief after TKA. LIA may achieve earlier ambulation compared with ACB. More high-quality RCTs are still required to make the final conclusion.

摘要

背景

目前,关于股神经阻滞(ACB)与局部浸润镇痛(LIA)在全膝关节置换术后疼痛管理中的效果,文献仍较少。本研究旨在进行相对可信和全面的评估,比较 ACB 与 LIA 在 TKA 后早期术后疼痛治疗中的效果。

方法

对 PubMed、MEDLINE、Cochrane、EMBASE 和 Web of Science 数据库中的已发表文献进行全面检索。本研究仅纳入随机临床试验(RCT)或准 RCT。主要结局是疼痛评分。次要结局指标包括阿片类药物消耗、功能结局(如计时起立行走测试和行走距离)和住院时间。

结果

纳入了 8 项 RCT,共 675 例患者。在 24 小时或 48 小时的疼痛评分、24 小时或 48 小时的总阿片类药物消耗以及住院时间方面,ACB 组与 LIA 组之间无统计学差异。然而,LIA 组在步行能力(P=0.03)和行走距离(P<0.00001)方面有更大的改善。

结论

两种治疗方法在 TKA 后均能提供相似的整体疼痛缓解效果。与 ACB 相比,LIA 可能更早实现步行。仍需要更多高质量的 RCT 来得出最终结论。

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