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经导管主动脉瓣置换术患者出院后护理碎片化与结局的关系:STS/ACC TVT 注册研究

Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry.

机构信息

Department of General Surgery, Duke University Medical Center, Durham, North Carolina.

Duke Clinical Research Institute, Durham, North Carolina.

出版信息

Am J Cardiol. 2019 Sep 15;124(6):912-919. doi: 10.1016/j.amjcard.2019.06.005. Epub 2019 Jun 27.

Abstract

Fragmented care following elective surgery has been associated with poor outcomes. The association between fragmented care and outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) is unknown. We examined patients who underwent TAVI from 2011 to 2015 at 374 sites in the STS/ACC TVT Registry, linked to Center for Medicare and Medicaid Services claims data. Fragmented care was defined as at least one readmission to a site other than the implanting TAVI center within 90 days after discharge, whereas continuous care was defined as readmission to the same implanting center. We compared adjusted 1-year outcomes, including stroke, bleeding, heart failure, mortality, and all-cause readmission in patients who received fragmented versus continuous care. Among 8,927 patients who received a TAVI between 2011 and 2015, 27.4% were readmitted within 90 days of discharge. Most patients received fragmented care (57.0%). Compared with the continuous care group, the fragmented care group was more likely to have severe chronic lung disease, cerebrovascular disease, and heart failure. States that had lower TAVI volume per Center for Medicare and Medicaid Services population had greater fragmentation. Patients living > 30 minutes from their TAVI center had an increased risk of fragmented care 1.07 (confidence interval [CI] 1.06 to 1.09, p < 0.001). After adjustment for comorbidities and procedural complications, fragmented care was associated with increased 1-year mortality (hazards ratio 1.18, CI 1.04 to 1.35, p = 0.010) and all-cause readmission (hazards ratio 1.08, CI 1.00 to 1.16, p = 0.051. In conclusion, fragmented readmission following TAVI is common, and is associated with increased 1-year mortality and readmission. Efforts to improve coordination of care may improve these outcomes and optimize long-term benefits yielded from TAVI.

摘要

择期手术后碎片化的护理与不良结局有关。接受经导管主动脉瓣植入术(TAVI)的患者中,碎片化护理与结局的关系尚不清楚。我们研究了 2011 年至 2015 年期间在 STS/ACC TVT 注册中心的 374 个地点接受 TAVI 的患者,这些数据与医疗保险和医疗补助服务索赔数据相关联。碎片化护理定义为出院后 90 天内至少有一次再入院至植入 TAVI 中心以外的其他地点,而连续护理则定义为再入院至同一植入中心。我们比较了接受碎片化护理与连续护理的患者在 1 年时的调整后结局,包括卒中和出血、心力衰竭、死亡率和全因再入院。在 2011 年至 2015 年间接受 TAVI 的 8927 名患者中,有 27.4%在出院后 90 天内再次入院。大多数患者接受了碎片化护理(57.0%)。与连续护理组相比,碎片化护理组更可能患有严重慢性肺部疾病、脑血管疾病和心力衰竭。接受 TAVI 的医疗保险和医疗补助服务患者人数较少的州,碎片化程度更高。距离 TAVI 中心超过 30 分钟的患者,发生碎片化护理的风险增加 1.07(置信区间 [CI] 1.06 至 1.09,p<0.001)。在调整了合并症和手术并发症后,碎片化护理与 1 年死亡率增加相关(风险比 1.18,CI 1.04 至 1.35,p=0.010)和全因再入院率增加(风险比 1.08,CI 1.00 至 1.16,p=0.051)。总之,TAVI 后再入院的碎片化很常见,并且与 1 年死亡率和再入院率增加相关。努力改善护理协调可能会改善这些结局,并优化 TAVI 带来的长期获益。

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