• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

磨牙严重受联合分又和骨内缺损影响的牙周再生的乳头保留瓣:基于注册队列的回顾性分析。

Papilla preservation flaps for periodontal regeneration of molars severely compromised by combined furcation and intrabony defects: Retrospective analysis of a registry-based cohort.

机构信息

European Research Group on Periodontology, Genoa, Italy.

Department of Oral Health Sciences, Section of Periodontology, KU Leuven, Leuven, Belgium.

出版信息

J Periodontol. 2020 Feb;91(2):165-173. doi: 10.1002/JPER.19-0010. Epub 2019 Aug 23.

DOI:10.1002/JPER.19-0010
PMID:31376157
Abstract

BACKGROUND

Furcation involvement and attachment loss are major predictors of tooth loss. The aim of this study was to describe specific designs for papilla preservation flaps (PPFs) and minimally invasive surgery to be used in compromised molars and report proof-of-principle data with 3 to 16-year follow-up in severely compromised molars due to the presence of combined furcation and intrabony defects.

METHODS

Forty-nine subjects with furcated molars and deep intrabony defects were treated with PPFs, application of periodontal regenerative devices. Improvement as a consequence of therapy was defined as tooth retention, reduction in horizontal and vertical furcation involvement, decrease in probing depths, and increases in clinical attachment level. Subjects were maintained with regular supportive periodontal care.

RESULTS

At 1 year, 100% of maxillary and 92% of mandibular molars showed improvements. Improvements were not observed in molars with baseline hypermobility: two mandibular molars with hypermobility were extracted at the 1-year follow-up. Improvement in vertical sub-classification was observed in 87.5% of maxillary and in 84.6% of mandibular molars. One-year improvements could be maintained over the 3 to 16-year follow-up.

CONCLUSIONS

PPFs and periodontal regeneration can be applied and provide clinical benefits to severely compromised molars due to the combined presence of furcation involvement and deep intrabony defects. These results were obtained in cases with an interdental peak of bone and gingival margin coronal to the furcation entrance in well-maintained and compliant subjects. Randomized controlled clinical trials with medium- to long-term follow-up are needed to confirm these findings.

摘要

背景

分叉区受累和附着丧失是牙齿丧失的主要预测因素。本研究的目的是描述用于受损磨牙的乳头保留瓣(PPF)和微创手术的特定设计,并报告在存在联合分叉和骨内缺损的严重受损磨牙中使用 3 至 16 年随访的原理验证数据。

方法

49 名分叉磨牙和深骨内缺损患者接受 PPF 治疗,应用牙周再生装置。治疗效果的改善定义为牙齿保留、水平和垂直分叉受累减少、探诊深度降低以及临床附着水平增加。患者接受常规牙周支持治疗。

结果

在 1 年时,上颌磨牙的 100%和下颌磨牙的 92%显示出改善。基线松动度较大的磨牙未观察到改善:2 颗下颌磨牙在 1 年随访时因松动而拔除。上颌磨牙中 87.5%和下颌磨牙中 84.6%的垂直亚组显示出改善。3 至 16 年的随访中可维持 1 年的改善。

结论

PPF 和牙周再生可应用于同时存在分叉受累和深骨内缺损的严重受损磨牙,并提供临床益处。这些结果是在保持良好和依从性的患者中存在牙槽嵴顶间骨和牙龈边缘位于分叉入口冠方的情况下获得的。需要进行具有中至长期随访的随机对照临床试验来证实这些发现。

相似文献

1
Papilla preservation flaps for periodontal regeneration of molars severely compromised by combined furcation and intrabony defects: Retrospective analysis of a registry-based cohort.磨牙严重受联合分又和骨内缺损影响的牙周再生的乳头保留瓣:基于注册队列的回顾性分析。
J Periodontol. 2020 Feb;91(2):165-173. doi: 10.1002/JPER.19-0010. Epub 2019 Aug 23.
2
Periodontal regeneration in humans using recombinant human platelet-derived growth factor-BB (rhPDGF-BB) and allogenic bone.使用重组人血小板衍生生长因子-BB(rhPDGF-BB)和同种异体骨进行人类牙周组织再生。
J Periodontol. 2003 Sep;74(9):1282-92. doi: 10.1902/jop.2003.74.9.1282.
3
A clinical comparison of the new attachment obtained by guided tissue regeneration and coronally positioned flap techniques in the management of human molar furcation defects.引导组织再生技术和冠向复位瓣技术获得的新型附着体治疗人类磨牙根分叉病变的临床比较
Aust Dent J. 1999 Mar;44(1):31-9. doi: 10.1111/j.1834-7819.1999.tb00533.x.
4
Periodontal regeneration - furcation defects: a systematic review from the AAP Regeneration Workshop.牙周组织再生——根分叉病变:美国牙周病学会再生研讨会的系统评价
J Periodontol. 2015 Feb;86(2 Suppl):S108-30. doi: 10.1902/jop.2015.130677.
5
The predictive performance of surgical treatment in upper molars with combined bony defect and furcation involvement: a retrospective cohort study.上颌磨牙伴有骨缺损和分叉受累的手术治疗预测效果:一项回顾性队列研究。
BMC Oral Health. 2022 May 6;22(1):156. doi: 10.1186/s12903-022-02196-0.
6
Multivariate outcome evaluation of furcation-involved molars treated with non-surgical mechanical therapy alone or combined with open flap debridement: A retrospective study.单独采用非手术机械治疗或联合开放性瓣清创术治疗根分叉病变磨牙的多因素结果评估:一项回顾性研究。
J Periodontol. 2022 May;93(5):673-686. doi: 10.1002/JPER.21-0113. Epub 2021 Sep 23.
7
Factors influencing the outcome of regenerative therapy in mandibular Class II furcations: Part I.影响下颌Ⅱ类根分叉病变再生治疗效果的因素:第一部分
J Periodontol. 2003 Sep;74(9):1255-68. doi: 10.1902/jop.2003.74.9.1255.
8
Guided tissue regeneration for the treatment of periodontal intrabony and furcation defects. A systematic review.引导组织再生术治疗牙周骨内和根分叉病变的系统评价
Ann Periodontol. 2003 Dec;8(1):266-302. doi: 10.1902/annals.2003.8.1.266.
9
A blind randomized controlled pilot trial on recombinant human bone morphogenetic protein-2 in combination with a bioresorbable membrane on periodontal regeneration in mandibular molar furcation defects.一项关于重组人骨形态发生蛋白-2联合可吸收膜在下颌磨牙分叉区缺损牙周再生中应用的盲法随机对照初步研究。
Quintessence Int. 2023 Feb 10;54(2):112-124. doi: 10.3290/j.qi.b3631815.
10
Guided tissue regeneration in Class II furcation involved maxillary molars: a controlled study of 8 split-mouth cases.上颌第二磨牙Ⅱ度根分叉病变的引导组织再生:8例半口对照研究。
J Periodontol. 1998 Sep;69(9):1020-6. doi: 10.1902/jop.1998.69.9.1020.

引用本文的文献

1
Resective and regenerative periodontal therapy for maxillary Class II furcation defect: A case report with 24-month follow-up.上颌Ⅱ度根分叉病变的切除性和再生性牙周治疗:一例24个月随访的病例报告
J Indian Soc Periodontol. 2024 Sep-Oct;28(5):581-586. doi: 10.4103/jisp.jisp_535_23. Epub 2025 Feb 26.
2
Periodontal Regeneration of Vital Poor Prognosis Teeth with Attachment Loss Involving the Root Apex: Two Cases with up to 5 Years Follow-Up.根尖附着丧失的活髓预后不良牙齿的牙周再生:两例长达5年的随访病例
Dent J (Basel). 2024 Jun 5;12(6):170. doi: 10.3390/dj12060170.
3
Management of Teeth with Grade 3 Endo-Periodontal Lesions by Combined Endodontic and Regenerative Periodontal Therapy.
采用牙髓牙周联合治疗方法对患有3级牙髓牙周病变的牙齿进行管理。
J Clin Med. 2023 Dec 23;13(1):93. doi: 10.3390/jcm13010093.
4
Clinical and radiographic evaluation of Bio-Oss granules and Bio-Oss Collagen in the treatment of periodontal intrabony defects: a retrospective cohort study.临床和影像学评价 Bio-Oss 颗粒和 Bio-Oss 胶原在牙周内骨缺损治疗中的应用:一项回顾性队列研究。
J Appl Oral Sci. 2024 Jan 5;32:e20230268. doi: 10.1590/1678-7757-2023-0268. eCollection 2024.
5
Periodontal regeneration by minimally invasive procedures and its influence on pulp status.微创程序进行牙周再生及其对牙髓状况的影响。
Acta Odontol Latinoam. 2023 Apr 29;36(1):53-57. doi: 10.54589/aol.36/1/53.
6
The influence of interradicular anatomy on the predictability of periodontal regenerative therapy of furcation defects: a retrospective, multicenter clinical study.根间解剖对牙周再生治疗分叉缺损可预测性的影响:一项回顾性、多中心临床研究。
Clin Oral Investig. 2023 Jul;27(7):3779-3786. doi: 10.1007/s00784-023-04995-3. Epub 2023 Apr 13.
7
Radiographic ratios for classifying furcation anatomy: proposal of a new evaluation method and an intra-rater and inter-rater operator reliability study.用于分类分叉解剖结构的放射比值:新评估方法的提出及一种观察者内和观察者间操作者可靠性研究。
Clin Oral Investig. 2023 Apr;27(4):1541-1546. doi: 10.1007/s00784-022-04774-6. Epub 2023 Feb 13.
8
Comparison between Conventional Modality Versus Cone-Beam Computer Tomography on the Assessment of Vertical Furcation in Molars.传统检查方式与锥形束计算机断层扫描在磨牙垂直根分叉病变评估中的比较
Diagnostics (Basel). 2022 Dec 29;13(1):106. doi: 10.3390/diagnostics13010106.
9
The predictive performance of surgical treatment in upper molars with combined bony defect and furcation involvement: a retrospective cohort study.上颌磨牙伴有骨缺损和分叉受累的手术治疗预测效果:一项回顾性队列研究。
BMC Oral Health. 2022 May 6;22(1):156. doi: 10.1186/s12903-022-02196-0.
10
Apical approach in periodontal reconstructive surgery with enamel matrix derivate and enamel matrix derivate plus bone substitutes: a randomized, controlled clinical trial.应用釉基质衍生物和釉基质衍生物联合骨替代材料行牙周组织再生术的尖牙区临床随机对照研究
Clin Oral Investig. 2022 Mar;26(3):2793-2805. doi: 10.1007/s00784-021-04256-1. Epub 2021 Nov 17.