Department of Radiology, Penn State Health, Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Department of Neurology, Pennsylvania State University-Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Clin Anat. 2019 Nov;32(8):1053-1060. doi: 10.1002/ca.23439. Epub 2019 Aug 14.
Function of cerebellum in control and coordination of motor function has been well established for several years. Recent functional magnetic resonance imaging (MRI) studies reveal activation of cerebellum with memory, speech and language tasks. We hypothesize that during every function in the brain signals are relayed to cerebellum. We seek to analyze cognitive, emotional and social functions of cerebellum in patients with brain tumors and epilepsy utilizing functional Magnetic Resonance Imaging. Fifty-one consecutive adult patients who underwent functional MRI examination were retrospectively analyzed for various activation patterns involving cerebellum. The neuropsychological battery of tasks assessed motor, language, memory, visual and auditory functions. Cognitive ability of all participants was assessed by Montreal cognitive assessment (MOCA). Patterns were analyzed for specific lobes and locations in the cerebellum. We found that simultaneous cerebellar activation is a consistent finding with brain activation during every functional MRI task that we tested except visual task. The patterns of functional MRI cerebellar activation were similar in both patient subgroups and control subjects compared to previously described patterns in normal subjects. Clin. Anat. 32:1053-1060, 2019. © 2019 Wiley Periodicals, Inc.
小脑在运动功能的控制和协调中的作用已经得到了多年的证实。最近的功能磁共振成像（fMRI）研究表明，小脑在记忆、言语和语言任务中被激活。我们假设，在大脑的每一个功能中，信号都会被传递到小脑。我们试图利用功能磁共振成像分析脑瘤和癫痫患者的小脑的认知、情感和社会功能。对 51 例连续接受功能磁共振成像检查的成年患者进行回顾性分析，以研究涉及小脑的各种激活模式。神经心理学测试任务评估了运动、语言、记忆、视觉和听觉功能。所有参与者的认知能力都通过蒙特利尔认知评估（MOCA）进行评估。分析了小脑特定叶和位置的模式。我们发现，除了视觉任务外，小脑在我们测试的每一个功能磁共振成像任务中与大脑同时激活是一个一致的发现。与正常受试者中描述的模式相比，患者亚组和对照组的 fMRI 小脑激活模式相似。临床解剖学 32:1053-1060, 2019。 Wiley Periodicals, Inc.
