• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

癫痫患者的认知障碍:以蒙特利尔认知评估量表(MoCA)作为筛查工具

Cognitive impairment in people with epilepsy: Montreal Cognitive Assessment (MoCA) as a screening tool.

作者信息

Novak Ajda, Vizjak Karmen, Gacnik Albin, Rakusa Martin

机构信息

Divison of Neurology, University Medical Centre Maribor, Maribor, Slovenia.

出版信息

Acta Neurol Belg. 2023 Apr;123(2):451-456. doi: 10.1007/s13760-022-02046-4. Epub 2022 Aug 4.

DOI:10.1007/s13760-022-02046-4
PMID:35925540
Abstract

OBJECTIVES

Although cognitive impairment is common in people with epilepsy, it is often neglected in outpatient clinics. MoCA is a simple and reliable test, which was validated for the cognitive screening of Alzheimer's and vascular dementia. The aim of our study was to evaluate MoCA as a tool for a cognitive screening of people with epilepsy.

METHODS

Our study included 50 people with epilepsy and 46 healthy individuals. All participants took the Slovenian version of the MoCA. Mean age, education and MoCA scores were compared between the two groups.

RESULTS

There was no significant difference between people with epilepsy and the controls in age (47.6, SD 18.1 vs 50.9, SD 14.0 years) or education (12.8, SD 2.8 vs 13.4, SD 2.8 years). People with epilepsy had significantly lower total MoCA scores than did the controls (23.3, SD 4.5 vs 27.5, SD 1.9 points; p < 0.001).

CONCLUSIONS

People with epilepsy achieved a lower score in several cognitive domains compared to the control group. MoCA can be used as an appropriate screening tool for cognitive impairment in people with epilepsy in the outpatient clinic. For a more accurate evaluation, neuropsychological assessments should be used.

摘要

目的

尽管认知障碍在癫痫患者中很常见,但在门诊中却常常被忽视。蒙特利尔认知评估量表(MoCA)是一种简单可靠的测试,已被验证可用于阿尔茨海默病和血管性痴呆的认知筛查。我们研究的目的是评估MoCA作为癫痫患者认知筛查工具的有效性。

方法

我们的研究纳入了50例癫痫患者和46名健康个体。所有参与者均接受了斯洛文尼亚语版的MoCA测试。比较了两组之间的平均年龄、受教育程度和MoCA得分。

结果

癫痫患者与对照组在年龄(47.6,标准差18.1岁 vs 50.9,标准差14.0岁)或受教育程度(12.8,标准差2.8年 vs 13.4,标准差2.8年)方面没有显著差异。癫痫患者的MoCA总分显著低于对照组(23.3,标准差4.5分 vs 27.5,标准差1.9分;p < 0.001)。

结论

与对照组相比,癫痫患者在几个认知领域的得分较低。MoCA可作为门诊癫痫患者认知障碍的合适筛查工具。为了进行更准确的评估,应使用神经心理学评估。

相似文献

1
Cognitive impairment in people with epilepsy: Montreal Cognitive Assessment (MoCA) as a screening tool.癫痫患者的认知障碍:以蒙特利尔认知评估量表(MoCA)作为筛查工具
Acta Neurol Belg. 2023 Apr;123(2):451-456. doi: 10.1007/s13760-022-02046-4. Epub 2022 Aug 4.
2
Validity of the MoCA as a cognitive screening tool in epilepsy: Are there implications for global care and research?MoCA 作为一种认知筛查工具在癫痫中的有效性:这对全球的护理和研究有何影响?
Epilepsia Open. 2024 Aug;9(4):1526-1537. doi: 10.1002/epi4.12991. Epub 2024 Jun 14.
3
Cognitive changes in patients with epilepsy identified through the MoCA test during neurology outpatient consultation.在神经科门诊就诊时,通过 MoCA 测试发现的癫痫患者认知变化。
Epilepsy Behav. 2021 Sep;122:108158. doi: 10.1016/j.yebeh.2021.108158. Epub 2021 Jun 25.
4
The validity of the Montreal cognitive assessment (MoCA) for the screening of vascular cognitive impairment after ischemic stroke.蒙特利尔认知评估量表(MoCA)在缺血性脑卒中后血管性认知障碍筛查中的有效性。
Acta Neurol Belg. 2020 Jun;120(3):681-685. doi: 10.1007/s13760-020-01330-5. Epub 2020 Mar 19.
5
Comparative study of two Chinese versions of Montreal Cognitive Assessment for Screening of Mild Cognitive Impairment.用于筛查轻度认知障碍的两种中文版蒙特利尔认知评估量表的比较研究
Appl Neuropsychol Adult. 2021 Jan-Feb;28(1):88-93. doi: 10.1080/23279095.2019.1602530. Epub 2019 Apr 23.
6
Development and validation of the Montreal cognitive assessment for people with hearing impairment (MoCA-H).发展和验证用于听力障碍人群的蒙特利尔认知评估(MoCA-H)。
J Am Geriatr Soc. 2023 May;71(5):1485-1494. doi: 10.1111/jgs.18241. Epub 2023 Feb 1.
7
Validity of the Montreal Cognitive Assessment Screener in Adolescents and Young Adults With and Without Congenital Heart Disease.蒙特利尔认知评估筛查工具在患有和未患有先天性心脏病的青少年及青年中的有效性。
Nurs Res. 2017 May/Jun;66(3):222-230. doi: 10.1097/NNR.0000000000000192.
8
Screening for cognitive impairment in systemic lupus erythematosus: Application of the Montreal Cognitive Assessment (MoCA) in a Greek patient sample.系统性红斑狼疮认知障碍筛查:蒙特利尔认知评估(MoCA)在希腊患者样本中的应用。
Lupus. 2021 Dec;30(14):2237-2247. doi: 10.1177/09612033211061062. Epub 2021 Dec 3.
9
Accuracy and Psychometric Properties of the Brazilian Version of the Montreal Cognitive Assessment as a Brief Screening Tool for Mild Cognitive Impairment and Alzheimer's Disease in the Initial Stages in the Elderly.《蒙特利尔认知评估巴西版作为老年人轻度认知障碍和阿尔茨海默病初始阶段简易筛查工具的准确性和心理测量学特性》
Dement Geriatr Cogn Disord. 2019;47(4-6):366-374. doi: 10.1159/000501308. Epub 2019 Aug 29.
10
A validation study of the Hong Kong version of Montreal Cognitive Assessment (HK-MoCA) in Chinese older adults in Hong Kong.香港版蒙特利尔认知评估量表(HK-MoCA)在香港华人老年人中的效度研究。
Hong Kong Med J. 2014 Dec;20(6):504-10. doi: 10.12809/hkmj144219. Epub 2014 Aug 15.

引用本文的文献

1
REST/NRSF Regulation of Epilepsy and Cognitive Impairment: Mechanisms and EEG Correlations.REST/NRSF对癫痫和认知障碍的调控:机制及脑电图相关性
Mol Neurobiol. 2025 Jul 17. doi: 10.1007/s12035-025-05138-3.
2
Can MOCA Be Applied for Rough Cognitive Assessment in Patients with Epilepsy in Mongolia?蒙特利尔认知评估量表(MOCA)能否应用于蒙古癫痫患者的简易认知评估?
J Clin Med. 2025 May 12;14(10):3372. doi: 10.3390/jcm14103372.
3
Alzheimer's Disease and Epilepsy: Exploring Shared Pathways and Promising Biomarkers for Future Treatments.

本文引用的文献

1
Cognitive Impairment in People with Epilepsy.癫痫患者的认知障碍
J Clin Med. 2022 Jan 5;11(1):267. doi: 10.3390/jcm11010267.
2
Dysphoria and Irritability-Diagnostic Pitfalls in the Assessment of Interictal Dysphoric Disorder in Epilepsy.烦躁不安与易怒——癫痫发作间期烦躁障碍评估中的诊断陷阱
J Clin Med. 2021 Oct 8;10(19):4624. doi: 10.3390/jcm10194624.
3
Multiple Comorbidity Profile of Psychiatric Disorders in Epilepsy.癫痫患者精神障碍的多重共病情况
阿尔茨海默病与癫痫:探索共同通路及未来治疗的潜在生物标志物
J Clin Med. 2024 Jul 1;13(13):3879. doi: 10.3390/jcm13133879.
4
Validity of the MoCA as a cognitive screening tool in epilepsy: Are there implications for global care and research?MoCA 作为一种认知筛查工具在癫痫中的有效性:这对全球的护理和研究有何影响?
Epilepsia Open. 2024 Aug;9(4):1526-1537. doi: 10.1002/epi4.12991. Epub 2024 Jun 14.
5
The assessment of the impact of antiepileptic drugs on cognitive functions via N-200/P-300 potentials and neuropsychological measures.通过 N-200/P-300 电位和神经心理学测量评估抗癫痫药物对认知功能的影响。
Neurol Sci. 2024 Oct;45(10):5011-5021. doi: 10.1007/s10072-024-07606-5. Epub 2024 May 25.
6
Alzheimer's disease and epilepsy: shared neuropathology guides current and future treatment strategies.阿尔茨海默病与癫痫:共同的神经病理学指导当前及未来的治疗策略。
Front Neurol. 2023 Oct 23;14:1241339. doi: 10.3389/fneur.2023.1241339. eCollection 2023.
7
An objective model for diagnosing comorbid cognitive impairment in patients with epilepsy based on the clinical-EEG functional connectivity features.基于临床脑电图功能连接特征诊断癫痫患者共病认知障碍的客观模型
Front Neurosci. 2023 Jan 12;16:1060814. doi: 10.3389/fnins.2022.1060814. eCollection 2022.
J Clin Med. 2021 Sep 11;10(18):4104. doi: 10.3390/jcm10184104.
4
Cognitive changes in patients with epilepsy identified through the MoCA test during neurology outpatient consultation.在神经科门诊就诊时,通过 MoCA 测试发现的癫痫患者认知变化。
Epilepsy Behav. 2021 Sep;122:108158. doi: 10.1016/j.yebeh.2021.108158. Epub 2021 Jun 25.
5
Functional magnetic resonance imaging based on Chinese tasks to protect language function in epileptics.基于中文任务的功能磁共振成像保护癫痫患者的语言功能。
Brain Behav. 2021 Feb;11(2):e01979. doi: 10.1002/brb3.1979. Epub 2020 Dec 30.
6
Altered White Matter Structural Network in Frontal and Temporal Lobe Epilepsy: A Graph-Theoretical Study.额叶和颞叶癫痫中白质结构网络的改变:一项基于图论的研究
Front Neurol. 2020 Jun 17;11:561. doi: 10.3389/fneur.2020.00561. eCollection 2020.
7
MoCA as a cognitive assessment tool for absence status epilepticus.MoCA 作为一种用于失神发作状态的认知评估工具。
Epileptic Disord. 2020 Apr 1;22(2):229-232. doi: 10.1684/epd.2020.1149.
8
Correlation of levetiracetam concentration in peripheral blood mononuclear cells with clinical efficacy: A sensitive monitoring biomarker in patients with epilepsy.外周血单个核细胞中左乙拉西坦浓度与临床疗效的相关性:癫痫患者的一种敏感监测生物标志物。
Seizure. 2020 May;78:71-77. doi: 10.1016/j.seizure.2020.03.009. Epub 2020 Mar 18.
9
The validity of the Montreal cognitive assessment (MoCA) for the screening of vascular cognitive impairment after ischemic stroke.蒙特利尔认知评估量表(MoCA)在缺血性脑卒中后血管性认知障碍筛查中的有效性。
Acta Neurol Belg. 2020 Jun;120(3):681-685. doi: 10.1007/s13760-020-01330-5. Epub 2020 Mar 19.
10
Cognitive impairment profile differences in patients with psychogenic non-epileptic seizures and epilepsy patients with generalized seizures.心理性非癫痫发作患者与全身性癫痫发作患者的认知障碍特征差异。
Neurol Res. 2020 Mar;42(3):179-188. doi: 10.1080/01616412.2020.1716468. Epub 2020 Jan 23.