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癫痫患者的认知障碍:以蒙特利尔认知评估量表(MoCA)作为筛查工具

Cognitive impairment in people with epilepsy: Montreal Cognitive Assessment (MoCA) as a screening tool.

作者信息

Novak Ajda, Vizjak Karmen, Gacnik Albin, Rakusa Martin

机构信息

Divison of Neurology, University Medical Centre Maribor, Maribor, Slovenia.

出版信息

Acta Neurol Belg. 2023 Apr;123(2):451-456. doi: 10.1007/s13760-022-02046-4. Epub 2022 Aug 4.

Abstract

OBJECTIVES

Although cognitive impairment is common in people with epilepsy, it is often neglected in outpatient clinics. MoCA is a simple and reliable test, which was validated for the cognitive screening of Alzheimer's and vascular dementia. The aim of our study was to evaluate MoCA as a tool for a cognitive screening of people with epilepsy.

METHODS

Our study included 50 people with epilepsy and 46 healthy individuals. All participants took the Slovenian version of the MoCA. Mean age, education and MoCA scores were compared between the two groups.

RESULTS

There was no significant difference between people with epilepsy and the controls in age (47.6, SD 18.1 vs 50.9, SD 14.0 years) or education (12.8, SD 2.8 vs 13.4, SD 2.8 years). People with epilepsy had significantly lower total MoCA scores than did the controls (23.3, SD 4.5 vs 27.5, SD 1.9 points; p < 0.001).

CONCLUSIONS

People with epilepsy achieved a lower score in several cognitive domains compared to the control group. MoCA can be used as an appropriate screening tool for cognitive impairment in people with epilepsy in the outpatient clinic. For a more accurate evaluation, neuropsychological assessments should be used.

摘要

目的

尽管认知障碍在癫痫患者中很常见,但在门诊中却常常被忽视。蒙特利尔认知评估量表(MoCA)是一种简单可靠的测试,已被验证可用于阿尔茨海默病和血管性痴呆的认知筛查。我们研究的目的是评估MoCA作为癫痫患者认知筛查工具的有效性。

方法

我们的研究纳入了50例癫痫患者和46名健康个体。所有参与者均接受了斯洛文尼亚语版的MoCA测试。比较了两组之间的平均年龄、受教育程度和MoCA得分。

结果

癫痫患者与对照组在年龄(47.6,标准差18.1岁 vs 50.9,标准差14.0岁)或受教育程度(12.8,标准差2.8年 vs 13.4,标准差2.8年)方面没有显著差异。癫痫患者的MoCA总分显著低于对照组(23.3,标准差4.5分 vs 27.5,标准差1.9分;p < 0.001)。

结论

与对照组相比,癫痫患者在几个认知领域的得分较低。MoCA可作为门诊癫痫患者认知障碍的合适筛查工具。为了进行更准确的评估,应使用神经心理学评估。

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