风湿性疾病的肺部病理学。

Pulmonary Pathology in Rheumatic Disease.

机构信息

Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

Clin Chest Med. 2019 Sep;40(3):667-677. doi: 10.1016/j.ccm.2019.05.011.

DOI:10.1016/j.ccm.2019.05.011

Abstract

The pathology of the pulmonary manifestations of rheumatoid diseases is characterized by its histologic heterogeneity and overlap with other pulmonary diseases. All anatomic compartments are vulnerable; thus, the morphologic changes vary according to the predominant region involved. Furthermore, the histologic patterns of injury are not unique to rheumatic diseases, given their resemblance to those seen in idiopathic forms, or in lung disease associated with other conditions. The patterns of interstitial lung disease, airway disorders, pleural processes, and vascular manifestations are described. The histopathology of selected entities, including the main vasculitides affecting the lung, and Ig G4-related disease are discussed.

摘要

类风湿疾病肺部表现的病理学特征为其组织学异质性，且与其他肺部疾病存在重叠。所有解剖部位均易受累；因此，形态学改变根据主要受累区域而有所不同。此外，鉴于其与特发性疾病或与其他疾病相关的肺部疾病中所见的形态学改变相似，损伤的组织学模式并非风湿性疾病所特有。间质性肺疾病、气道疾病、胸膜过程和血管表现的模式均有描述。还讨论了包括主要累及肺部的血管炎和 IgG4 相关疾病在内的一些特定实体的组织病理学。