Gabrilovich D I, Shalygina N B, Zmyzgova A V, Musarov A L, Kuznetsova E N
Zh Mikrobiol Epidemiol Immunobiol. 1988 Apr(4):70-4.
A decrease in the capacity of lymphocytes for rosette formation, accompanied by a rise in the leukocyte count, has been found in patients with the severe form of hepatitis non A, non B. Neutrophils in these patients have shown a tendency towards an increased rosette formation. All altered characteristics normalized by the period of convalescence. As noted in this investigation, a considerable increase in the leukocyte count, along with an increase in the number of active rosette-forming neutrophils and a decrease in the capacity of leukocytes for rosette formation, is an unfavorable sign predicting the possibility of acute hepatic encephalopathy.
在非甲非乙型重症肝炎患者中发现,淋巴细胞形成玫瑰花结的能力下降,同时白细胞计数升高。这些患者的中性粒细胞显示出形成玫瑰花结的趋势增加。所有改变的特征在恢复期恢复正常。正如本研究中所指出的,白细胞计数显著增加,同时活性玫瑰花结形成中性粒细胞数量增加以及白细胞形成玫瑰花结的能力下降,是预测急性肝性脑病可能性的不利迹象。