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[牙源性肿瘤和牙源性囊肿:4181例临床与病理分析]

[Odontogenic tumors and odontogenic cysts: a clinical and pathological analysis of 4 181 cases].

作者信息

Su Y K, Wang J, Zhang T F, Zhang Z B

机构信息

Department of Pathology, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.

Department of Medical Administration, School and Hospital of Stomatology, Jilin University, Changchun 130021, China.

出版信息

Zhonghua Kou Qiang Yi Xue Za Zhi. 2019 Aug 9;54(8):546-552. doi: 10.3760/cma.j.issn.1002-0098.2019.08.009.

Abstract

To investigate the incidence and constituent ratio of odontogenic tumors or odontogenic cysts in School and Hospital of Stomatology, Jilin University and to provide the reference for the clinical treatment. According to the WHO 2017 histological classification criteria, the pathological data of 4181 patients diagnosed as odontogenic tumors or odontogenic cysts in the Department of Pathology, Jilin University Stomatological Hospital from January 1961 to December 2017 were collected. Statistical analysis of the pathological types, gender, age and location of various tumors and cysts was conducted. Of 4 181 cases, 1 055 were tumors and 3 126 were cysts. Among odontogenic tumors, benign tumors accounted for 96.11% (1 014/1 055), and malignant tumors accounted for 3.89% (41/1 055). The most common pathological type of odontogenic tumors was ameloblastoma [53.27% (562/1 055)], followed by cemento-ossifying fibroma [21.23% (224/1 055)] and odontoma [12.99% (137/1 055)]. The male-female ratio was 1∶1.04. The high-risk ages were 10-39. Maxilla-mandible ratio was 1∶2.85.As for cysts, radicular cysts [50.45% (1 577/3 126)] was the most common pathological type, followed by odontogenic keratocyst [25.59% (800/3 126)] and dentigerous cysts [21.56% (674/3 126)]. The male-female ratio was 1.37∶1. The high-risk ages were 20-49. Maxilla-mandible ratio was 1.37∶1. There was no gender preference for odontogenic tumors in Jilin Province area in the 57 years. The majority tumors occurred in the radicular. The most common pathological type was ameloblastoma. As for odontogenic cysts, males showed a higher incidence and the majority cysts occurred in the maxilla. The most common pathological type was radicular cysts.

摘要

调查吉林大学口腔医院牙源性肿瘤或牙源性囊肿的发病率及构成比,为临床治疗提供参考依据。依据世界卫生组织2017年组织学分类标准,收集吉林大学口腔医院病理科1961年1月至2017年12月诊断为牙源性肿瘤或牙源性囊肿的4181例患者的病理资料,对各种肿瘤及囊肿的病理类型、性别、年龄及部位进行统计分析。4181例中,肿瘤1055例,囊肿3126例。牙源性肿瘤中,良性肿瘤占96.11%(1014/1055),恶性肿瘤占3.89%(41/1055)。牙源性肿瘤最常见的病理类型为成釉细胞瘤[53.27%(562/1055)],其次为牙骨质-骨化性纤维瘤[21.23%(224/1055)]和牙瘤[12.99%(137/1055)]。男女比例为1∶1.04。高危年龄为10~39岁。上颌与下颌比例为1∶2.85。牙源性囊肿中,根尖囊肿[50.45%(1577/3126)]是最常见的病理类型,其次为牙源性角化囊肿[25.59%(800/3126)]和含牙囊肿[21.56%(674/3126)]。男女比例为1.37∶1。高危年龄为20~49岁。上颌与下颌比例为1.37∶1。吉林省地区57年来牙源性肿瘤无性别倾向,多数肿瘤发生于根尖区,最常见的病理类型为成釉细胞瘤。牙源性囊肿男性发病率较高,多数囊肿发生于上颌,最常见的病理类型为根尖囊肿。

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