Ryttman H, Thebo P, Gustavsson I
Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala.
Anim Genet. 1988;19(2):197-200. doi: 10.1111/j.1365-2052.1988.tb00807.x.
Fibroblasts from a pig with a spontaneous reciprocal translocation involving chromosome 7, were used to prepare a set of pig-mouse somatic cell hybrids. The isozyme analysis strongly indicated that in pigs, the NP (nucleoside phosphorylase) gene is located on the distal part of the long arm of chromosome 7, (q21----qter), while the MPI (mannose phosphate isomerase) gene is in the region q21----pter. This confirmed previously reported chromosomal assignment of these genes in pigs and that this synteny has been evolutionarily conserved in several different animal species.
从一头患有涉及7号染色体的自发相互易位的猪身上获取成纤维细胞，用于制备一组猪 - 小鼠体细胞杂种。同工酶分析有力地表明，在猪中，NP（核苷磷酸化酶）基因位于7号染色体长臂的远端（q21----qter），而MPI（磷酸甘露糖异构酶）基因位于q21----pter区域。这证实了先前报道的猪中这些基因的染色体定位，并且这种同线性在几种不同的动物物种中在进化上是保守的。
