母体营养过度对胎儿宫内生长迟缓的影响。
Effect of maternal hyperalimentation on intrauterine growth retardation.
作者信息
De Prins F, Hill D J, Milner R D, Van Assche A
机构信息
Department of Developmental Biology, Catholic University of Leuven, Belgium.
出版信息
Arch Dis Child. 1988 Jul;63(7 Spec No):733-6. doi: 10.1136/adc.63.7_spec_no.733.
The effect of maternal hyperalimentation on intrauterine growth retardation was studied by performing unilateral uterine vessel ligation on day 17 in Wistar rats. Test animals were given food supplements by gavage for three days postoperatively whereas control animals received saline. The caloric intake and weight gain of the test dams was significantly greater than that of the controls from days 17 to 20 but not over the longer period, day 14 to 23. The survival and growth of fetuses in the unoperated horn were similar in test and control rats. Fetal survival in the ligated horn was doubled by maternal food supplementation but the growth and development of the survivors were not improved.
通过对17日龄的Wistar大鼠进行单侧子宫血管结扎，研究了母体过度营养对宫内生长迟缓的影响。术后三天，通过灌胃给予试验动物食物补充剂，而对照动物则给予生理盐水。从第17天到第20天，试验母鼠的热量摄入和体重增加显著高于对照组，但在更长的时间段（第14天到第23天）并非如此。在试验组和对照组大鼠中，未手术侧子宫角内胎儿的存活和生长情况相似。通过母体食物补充，结扎侧子宫角内胎儿的存活率提高了一倍，但存活胎儿的生长和发育并未得到改善。
Zotero 插件