Schwartz Rebecca M, Ornstein Katherine A, Liu Bian, Alpert Naomi, Bevilacqua Kristin G, Taioli Emanuela
Northwell Health, Occupational Medicine, Epidemiology and Prevention , Great Neck , NY , USA.
Institute for Translational Epidemiology, Department of Population Health Science and Policy, The Icahn School of Medicine at Mount Sinai , New York , NY , USA.
Cancer Invest. 2019;37(7):299-310. doi: 10.1080/07357907.2019.1645160. Epub 2019 Aug 5.
Age-related decreases in Quality of Life (QoL) are often compounded by comorbidities, including cancer. This study aimed to examine QoL changes before and after a new cancer diagnosis using data from the National Health and Aging Trend Study (NHATS), linked to Medicare claims ( = 136). There was a significant increase in the relative odds of fair/poor self-reported health and needing help with Activities of Daily Living. There was also a marginal increase in depression, but no change in anxiety or pain scores. Results underscore importance of considering pre-cancer QoL when making treatment decisions for older adult cancer patients.
与年龄相关的生活质量(QoL)下降往往因包括癌症在内的合并症而加剧。本研究旨在利用与医疗保险理赔相关的国家健康与老龄化趋势研究(NHATS)数据(n = 136),考察新癌症诊断前后的生活质量变化。自我报告健康状况为一般/较差以及在日常生活活动方面需要帮助的相对几率显著增加。抑郁也略有增加,但焦虑或疼痛评分没有变化。研究结果强调了在为老年癌症患者做出治疗决策时考虑癌症前生活质量的重要性。