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多发性非家族性单侧毛发上皮瘤：1例报告并文献综述

Multiple Nonfamilial Unilateral Trichoepitheliomas: Report of a Case-Mini Review of the Literature.

作者信息

Mandekou-Lefaki I, Theodosiou G, Delli F-S, Oikonomou D, Papageorgiou M

机构信息

Dermatology, Geniki Kliniki-Euromedica Private Hospital, Thessaloniki, Greece.

Department of Dermatology, Skåne Univeristy of Skåne, Malmö, Sweden.

出版信息

Case Rep Dermatol Med. 2019 Jul 14;2019:6821854. doi: 10.1155/2019/6821854. eCollection 2019.

DOI:10.1155/2019/6821854
PMID:31380124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6662247/
Abstract

Trichoepitheliomas are benign skin tumors with follicular differentiation that present most commonly as solitary lesions. They can also present as multiple centrofacial papules due to several mutations in the CYLD gene. Multiple unilateral trichoepitheliomas in a linear or dermatomal distribution may rarely be seen. Herein, we report a case of multiple unilateral trichoepitheliomas on the face of a healthy 34-year-old woman of Caucasian origin.

摘要

毛发上皮瘤是一种具有毛囊分化的良性皮肤肿瘤，最常见表现为孤立性损害。由于CYLD基因的多种突变，它们也可表现为多发性面部丘疹。线性或皮节分布的多发性单侧毛发上皮瘤则很少见。在此，我们报告一例发生于一名34岁健康白种女性面部的多发性单侧毛发上皮瘤病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/0dc460f052fd/CRIDM2019-6821854.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/88500df70c87/CRIDM2019-6821854.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/9575dd71f604/CRIDM2019-6821854.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/7710e512e7e3/CRIDM2019-6821854.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/0dc460f052fd/CRIDM2019-6821854.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/88500df70c87/CRIDM2019-6821854.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/9575dd71f604/CRIDM2019-6821854.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/7710e512e7e3/CRIDM2019-6821854.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a4d/6662247/0dc460f052fd/CRIDM2019-6821854.004.jpg

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本文引用的文献

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Dermatol Ther. 2017 Mar;30(2). doi: 10.1111/dth.12458. Epub 2017 Jan 30.
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Multiple Familial Trichoepithelioma Successfully Treated With CO Laser and Imiquimod.
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Nonfamilial Multiple Trichoepithelioma: Few and Far Between.非家族性多发性毛发上皮瘤：罕见。
Indian J Dermatol. 2016 Jan-Feb;61(1):78-80. doi: 10.4103/0019-5154.174030.
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A rare case of sporadic multiple trichoepitheliomas.一例罕见的散发性多发性毛发上皮瘤。
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Multiple familial trichoepithelioma with malignant transformation.伴恶性转化的多发性家族性毛发上皮瘤
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Diagnostic utility of immunohistochemistry in distinguishing trichoepithelioma and basal cell carcinoma: evaluation using tissue microarray samples.免疫组织化学在鉴别毛发上皮瘤和基底细胞癌中的诊断效用：组织微阵列样本评估。
Mod Pathol. 2012 Oct;25(10):1345-53. doi: 10.1038/modpathol.2012.96. Epub 2012 Jun 8.
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Treatment of cutaneous tumors with topical 5% imiquimod cream.局部应用 5%咪喹莫特乳膏治疗皮肤肿瘤。
Clinics (Sao Paulo). 2009;64(10):961-6. doi: 10.1590/S1807-59322009001000005.
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10
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