Dissanayaka D W V N, Dassanayaka D K B, Jayasooriya P R
Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Sri Lanka.
Oral and Maxillofacial Surgery Unit, Provincial General Hospital Badulla, Sri Lanka.
Case Rep Dent. 2020 Sep 7;2020:5648647. doi: 10.1155/2020/5648647. eCollection 2020.
Trichoepitheliomas (TE) are benign skin tumours of the pilosebaceous apocrine unit with follicular differentiation. Multiple familial trichoepithelioma (MFT) is a considerably rare condition inherited in an autosomal dominant pattern. We present a case of a 15-year-old male who presented with multiple papulo-nodular lesions in the central face and a family history of a similar type of lesions from his mother. Significance of consideration of various clinical differential diagnoses with serious pathological outcomes, strategies followed in the diagnosis including histopathological evaluation aided by immunohistochemical investigations, and subsequent challenges that may be faced in the management of MFT in light of the presentation with multiple facial papules are documented in this case report.
毛发上皮瘤（TE）是具有毛囊分化的皮脂腺顶泌汗腺单位的良性皮肤肿瘤。多发性家族性毛发上皮瘤（MFT）是一种相当罕见的常染色体显性遗传疾病。我们报告一例15岁男性病例，该患者面部中央出现多个丘疹结节性皮损，其母亲有类似皮损的家族史。本病例报告记录了考虑各种具有严重病理结果的临床鉴别诊断的意义、诊断中遵循的策略（包括借助免疫组化检查的组织病理学评估），以及鉴于该患者出现多发性面部丘疹，在MFT管理中可能面临的后续挑战。
