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碳纤维椎间融合器重建术治疗多节段颈椎病前路椎体次全切除术后的中期疗效

Carbon-fibre cage reconstruction in anterior cervical corpectomy for multilevel cervical spondylosis: mid-term outcomes.

作者信息

Cawley Derek T, Alzakri Abdulmajeed, Fujishiro Takashi, Kieser David C, Tavalaro Celeste, Boissiere Louis, Obeid Ibrahim, Pointillart Vincent, Vital Jean Marc, Gille Olivier

机构信息

l'Institut de la Colonne Vertébrale, Surgery Unit 1, 7ème étage, CHU Tripode Pellegrin, Bordeaux, France.

Department of Trauma & Orthopaedic Surgery, Tallaght University Hospital, Dublin, Ireland.

出版信息

J Spine Surg. 2019 Jun;5(2):251-258. doi: 10.21037/jss.2019.03.08.

Abstract

BACKGROUND

Mid-term clinical and radiological evaluation of a carbon-fiber cage in multilevel cervical spondylosis (MCS). Anterior cervical corpectomy and fusion (ACCF) using titanium mesh cages (TMC) has shown satisfactory outcomes, but with subsidence of up to 20%. Conventional long-fiber carbon fiber cages have shown a safe profile in discectomy/fusion (ACDF) but with minimal data in the setting of corpectomy.

METHODS

Retrospective review of a single centre multi-surgeon cohort of MCS patients from 2007-2012. Follow-up period was a minimum of 3.5 years, mean 6 years. Outcomes included peri-operative, clinical [Nurick, European Myelopathy, Visual Analogue Scores (VAS), modified Japanese Orthopaedic Association (mJOA) scores and radiographic (C2C7, Cobb & ROM angles)].

RESULTS

A total of 102 consecutive patients were included. Mean length of stay was 5.5 (SD 3.5) days, blood loss 322 (SD 358) mL and operative time 98 (SD 31) min. Corpectomy levels included 72 single-level ACCF and 30 multiple ACCF. Fourteen had peri-operative complications. Three patients required early cage revisions. Mean pain scores improved from VAS neck 4.6 to 2.6 (P<0.01) and VAS arm 5.1 to 2.0 (P<0.01). Mean Nurick score improved from 1.2 to 0.4/4 (P<0.01). Mean follow-up EMS was 15.9/18 and mJOA was 14.0/17. Seventy follow-up radiographs were obtained. Flexion-extension angulation differences of >3 mm across the instrumented level were present in 5 patients, all of which displayed fusion of either grade 1 or 2. 7 had C2C7 kyphosis. Severe subsidence (>3 mm) was seen in 9 cases (13%).

CONCLUSIONS

Mid-term outcomes of this carbon-fiber cage indicate that it is safe and durable for the treatment of MCS with a similar radiological profile to that of TMC.

摘要

背景

对碳纤维椎间融合器用于多节段颈椎病(MCS)的中期临床和影像学评估。使用钛网椎间融合器(TMC)进行前路颈椎椎体次全切除融合术(ACCF)已显示出令人满意的结果,但沉降率高达20%。传统的长纤维碳纤维椎间融合器在椎间盘切除/融合术(ACDF)中已显示出安全的特性,但在椎体次全切除术的情况下数据极少。

方法

回顾性分析2007年至2012年来自单一中心的多外科医生队列的MCS患者。随访期至少为3.5年,平均6年。结果包括围手术期、临床[Nurick分级、欧洲脊髓病量表、视觉模拟评分(VAS)、改良日本骨科协会(mJOA)评分]和影像学(C2C7、Cobb角和活动度)。

结果

共纳入102例连续患者。平均住院时间为5.5(标准差3.5)天,失血量为322(标准差358)毫升,手术时间为98(标准差31)分钟。椎体次全切除节段包括72例单节段ACCF和30例多节段ACCF。14例发生围手术期并发症。3例患者需要早期更换椎间融合器。平均疼痛评分从颈部VAS 4.6改善至2.6(P<0.01),手臂VAS从5.1改善至2.0(P<0.01)。平均Nurick评分从1.2改善至0.4/4(P<0.01)。平均随访时欧洲脊髓病量表评分为15.9/18,mJOA评分为14.0/17。获得70份随访X线片。5例患者在植入节段的屈伸角度差异>3毫米,所有这些患者均显示1级或2级融合。7例存在C2C7后凸畸形。9例(13%)出现严重沉降(>3毫米)。

结论

这种碳纤维椎间融合器的中期结果表明,其用于治疗MCS是安全且持久的,影像学表现与TMC相似。

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