Kabir Syed M R, Alabi J, Rezajooi Kia, Casey Adrian T H
Department of Spinal Surgery, The National Hospital for Neurology and Neurosurgery, London, UK.
Br J Neurosurg. 2010 Oct;24(5):542-6. doi: 10.3109/02688697.2010.503819.
Different types of cages have recently become available for reconstruction following anterior cervical corpectomy. We review the results using titanium mesh cages (TMC) and stackable CFRP (carbon fibre reinforced polymer) cages. Forty-two patients who underwent anterior cervical corpectomy between November 2001 and September 2008 were retrospectively reviewed. Pathologies included cervical spondylotic myelopathy (CSM), cervical radiculopathy, OPLL (ossified posterior longitudinal ligament), metastasis/primary bone tumour, rheumatoid arthritis and deformity correction. All patients were evaluated clinically and radiologically. Outcome was assessed on the basis of the Odom's criteria, neck disability index (NDI) and myelopathy disability index (MDI). Mean age was 60 years and mean follow-up was 1½ years. Majority of the patients had single-level corpectomy. Twenty-three patients had TMC cages while 19 patients had CFRP cages. The mean subsidence noted with TMC cage was 1.91 mm, while with the stackable CFRP cage it was 0.5 mm. This difference was statistically significant (p < 0.05). However, there was no statistically significant correlation noted between subsidence and clinical outcome (p > 0.05) or between subsidence and post-operative sagittal alignment (p > 0.05) in either of the groups. Three patients had significant subsidence (> 3 mm), one of whom was symptomatic. There were no hardware-related complications. On the basis of the Odom's criterion, 9 patients (21.4%) had an excellent outcome, 14 patients (33.3%) had a good outcome, 9 patients (21.4%) had a fair outcome and 5 patients (11.9%) had a poor outcome, i.e. symptoms and signs unchanged or exacerbated. Mean post-operative NDI was 26.27% and mean post-operative MDI was 19.31%. Fusion was noted in all 42 cases. Both TMC and stackable CFRP cages provide solid anterior column reconstruction with good outcome following anterior cervical corpectomy. However, more subsidence is noted with TMC cages though this might not significantly alter the clinical outcome unless the subsidence is significant (>3 mm).
近年来,不同类型的椎间融合器已可用于颈椎前路椎体次全切除术后的重建。我们回顾了使用钛网椎间融合器(TMC)和可堆叠碳纤维增强聚合物(CFRP)椎间融合器的结果。对2001年11月至2008年9月期间接受颈椎前路椎体次全切除术的42例患者进行了回顾性研究。病理类型包括脊髓型颈椎病(CSM)、神经根型颈椎病、后纵韧带骨化症(OPLL)、转移瘤/原发性骨肿瘤、类风湿关节炎和畸形矫正。所有患者均进行了临床和影像学评估。根据奥多姆标准、颈部功能障碍指数(NDI)和脊髓病功能障碍指数(MDI)评估结果。平均年龄为60岁,平均随访时间为1.5年。大多数患者为单节段椎体次全切除术。23例患者使用了TMC椎间融合器,19例患者使用了CFRP椎间融合器。TMC椎间融合器的平均下沉量为1.91mm,而可堆叠CFRP椎间融合器的平均下沉量为0.5mm。这种差异具有统计学意义(p<0.05)。然而,在两组中,下沉与临床结果之间(p>0.05)或下沉与术后矢状位对线之间(p>0.05)均未发现统计学意义上的相关性。3例患者出现明显下沉(>3mm),其中1例有症状。未发生与内固定相关的并发症。根据奥多姆标准,9例患者(21.4%)结果优秀,14例患者(33.3%)结果良好,9例患者(21.4%)结果一般,5例患者(11.9%)结果较差,即症状和体征未改变或加重。术后平均NDI为26.27%,术后平均MDI为19.31%。42例患者均实现了融合。TMC和可堆叠CFRP椎间融合器均可在前路颈椎椎体次全切除术后提供可靠的前柱重建,且效果良好。然而,TMC椎间融合器的下沉更为明显,不过除非下沉明显(>3mm),否则这可能不会显著改变临床结果。