Department of Psychiatry and Psychotherapy University Hospital Munich, LMU Munich, Nussbaumstraße 7, Munich 80336, Germany.
Department of Psychiatry and Psychotherapy University Hospital Munich, LMU Munich, Nussbaumstraße 7, Munich 80336, Germany.
Psychiatry Res. 2019 Oct;280:112505. doi: 10.1016/j.psychres.2019.112505. Epub 2019 Aug 1.
The use of methamphetamine is spreading globally and provokes the need for effective treatment options. Previous research showed increased psychiatric comorbidities in methamphetamine users, but its impact on treatment success is still unclear. This study investigates data from two German addiction rehabilitation centers including 108 methamphetamine using individuals. The participants were tested and interviewed at the beginning of the addiction treatment program and at the end of treatment after about six months. In total, 95% of the participants had at least another psychiatric diagnosis. At admission, substance related comorbid diagnoses (meaning abuse or addiction of other substances than methamphetamine) showed a significant effect on treatment dropout. Within the substance related diagnoses, the majority of participants (62%) suffered from cannabinoid dependency. Non-substance related comorbidities and the total number of comorbid diagnoses did not have an impact on treatment outcome. The most frequent non substance specific diagnosis at admission was a depressive disorder (15%). Diagnoses patients had at discharge did not show any effects on the treatment completion. Comparing diagnoses at admission and discharge revealed slight differences, which may rise from a better assessment at discharge due to the fact that clinicians got to know the patients better during the therapeutic process.
冰毒的使用在全球范围内蔓延，这引发了人们对有效治疗选择的需求。先前的研究表明，冰毒使用者存在更多的精神共病，但它对治疗成功的影响仍不清楚。本研究调查了来自德国两家戒毒康复中心的数据，其中包括 108 名使用冰毒的个体。参与者在戒毒治疗计划开始时和大约六个月后的治疗结束时接受测试和访谈。总共，95%的参与者至少还有另一个精神科诊断。在入院时，与物质相关的共病诊断（即滥用或成瘾于冰毒以外的其他物质）对治疗脱落有显著影响。在与物质相关的诊断中，大多数参与者（62%）患有大麻素依赖。非物质相关的共病和共病诊断的总数对治疗结果没有影响。入院时最常见的非物质特异性诊断是抑郁症（15%）。出院时患者的诊断没有显示出对治疗完成的任何影响。比较入院和出院时的诊断显示出一些细微的差异，这可能是由于在治疗过程中临床医生更好地了解了患者，因此在出院时的评估有所改善。
