Wiggenraad R, Ravasz L A, Probst-van Zuylen F E
Dep. Radiotherapie, University Hospital, Utrecht, Holland.
Int J Radiat Oncol Biol Phys. 1988 Sep;15(3):753-6. doi: 10.1016/0360-3016(88)90322-7.
The adjuvant postoperative irradiation is an efficient treatment method to diminish the chance on pelvic recurrences in high risk group patients having rectosigmoid or rectumcarcinomas Dukes B or C and/or in case of positive surgical margins. We reviewed the literature and our own patient material treated at the University Hospital Utrecht in the years 1980-1983. Our results are comparable with the results published in Boston. Because of the high percentage local recurrence in the perineum following APR, we changed our technique and dose. Our results from 1980-1983 and the technique and dose used since 1985 is described. We also recommend some preventive measures to lower the complication rate.
术后辅助放疗是一种有效的治疗方法，可降低乙状结肠直肠或直肠癌Dukes B或C期高危组患者以及手术切缘阳性患者盆腔复发的几率。我们回顾了文献以及1980年至1983年在乌得勒支大学医院治疗的自身患者资料。我们的结果与波士顿发表的结果相当。由于腹会阴联合切除术（APR）后会阴部局部复发率较高，我们改变了技术和剂量。描述了我们1980年至1983年的结果以及自1985年以来使用的技术和剂量。我们还推荐了一些预防措施以降低并发症发生率。
