Suppr超能文献

变应性鼻炎与分泌性中耳炎的相关性

Correlation between Allergic Rhinitis and Otitis Media with Effusion.

作者信息

Sharifian Mohammad Reza, Mahmoudi Mahmoud, Pourmomenarabi Babak, Keramati Mohammad Reza

机构信息

Department of Otorhinolaryngology-Head & Neck Surgery, Mashhad University of Medical Sciences, Mashhad, Iran.

Immunology Research Centre, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Iran J Otorhinolaryngol. 2019 Jul;31(105):209-215.

Abstract

INTRODUCTION

Otitis media with effusion (OME) is prevalent among children in such a way that it is the most common cause of hearing loss and surgery in childhood. Immunoglobulin E (IgE) mediated hypersensitivity has been proposed as a causative factor in the development of OME; however, there has been contrasting data in this regard. Therefore, the present study aimed to detect the possibilities of interconnection.

MATERIALS AND METHODS

In this study, 37 OME children were selected as the case group and 52 children were randomly chosen as the control group. Allergic rhinitis prevalence, serum total IgE concentration, serum eosinophil count, and nasal scraping cytology were evaluated in all the children. Furthermore, the skin prick test was performed in the OME group and suspected allergic rhinitis patients in the control group.

RESULTS

Allergic rhinitis prevalence was notably higher among OME patients than in the control group (P0.01). There were no remarkable differences in eosinophil counts and serum IgE concentrations in the two groups. Nasal smear eosinophils did not show any significant difference between the two groups; however, Appreciable difference was observed in the allergic rhinitis patients, compared to other OME patients (P0.004).

CONCLUSION

There may be a correlation between allergic rhinitis and development of OME. Therefore, it seems reasonable to examine allergic rhinitis patients for OME.

摘要

引言

分泌性中耳炎(OME)在儿童中很常见,是儿童听力丧失和手术的最常见原因。免疫球蛋白E(IgE)介导的超敏反应被认为是OME发病的一个致病因素;然而,这方面的数据存在矛盾。因此,本研究旨在检测两者之间相互关联的可能性。

材料与方法

在本研究中,选取37例OME患儿作为病例组,随机选取52例儿童作为对照组。对所有儿童评估变应性鼻炎患病率、血清总IgE浓度、血清嗜酸性粒细胞计数和鼻拭子细胞学检查。此外,对OME组和对照组中疑似变应性鼻炎的患者进行皮肤点刺试验。

结果

OME患者的变应性鼻炎患病率显著高于对照组(P<0.01)。两组的嗜酸性粒细胞计数和血清IgE浓度无显著差异。两组鼻涂片嗜酸性粒细胞无显著差异;然而,与其他OME患者相比,变应性鼻炎患者有明显差异(P<0.004)。

结论

变应性鼻炎与OME的发生之间可能存在关联。因此,对变应性鼻炎患者进行OME检查似乎是合理的。

相似文献

5
Increased nasal eosinophils in children with otitis media with effusion.中耳积液患儿鼻内嗜酸性粒细胞增多。
Otolaryngol Head Neck Surg. 1996 Nov;115(5):454-7. doi: 10.1177/019459989611500517.
8
Allergic diseases in children with otitis media with effusion.伴有中耳积液的儿童过敏性疾病。
Int J Pediatr Otorhinolaryngol. 2013 Feb;77(2):158-61. doi: 10.1016/j.ijporl.2012.09.039. Epub 2012 Dec 14.
10
Clinical characteristics of atelectatic eardrums and adhesive otitis media in children.儿童萎陷性鼓膜和粘连性中耳炎的临床特征。
Int J Pediatr Otorhinolaryngol. 2022 Aug;159:111188. doi: 10.1016/j.ijporl.2022.111188. Epub 2022 May 26.

引用本文的文献

2
V Brazilian Consensus on Rhinitis - 2024.第五届巴西鼻炎共识 - 2024年
Braz J Otorhinolaryngol. 2025 Jan-Feb;91(1):101500. doi: 10.1016/j.bjorl.2024.101500. Epub 2024 Sep 7.
7
Changes in symptoms of Eustachian tube dysfunction after nasal surgery.咽鼓管功能障碍症状在鼻部手术后的变化。
Eur Arch Otorhinolaryngol. 2022 Oct;279(10):5017-5023. doi: 10.1007/s00405-022-07344-4. Epub 2022 Mar 29.

本文引用的文献

2
Criteria of eosinophilia.嗜酸性粒细胞增多的标准。
Lancet. 1946 Feb 9;1(6389):195. doi: 10.1016/s0140-6736(46)91306-2.
8
Atopy in children with otitis media with effusion.分泌性中耳炎患儿的特应性
Clin Exp Allergy. 1998 May;28(5):591-6. doi: 10.1046/j.1365-2222.1998.00284.x.
9
Increased nasal eosinophils in children with otitis media with effusion.中耳积液患儿鼻内嗜酸性粒细胞增多。
Otolaryngol Head Neck Surg. 1996 Nov;115(5):454-7. doi: 10.1177/019459989611500517.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验