Katsafadou Angeliki I, Tsangaris George Th, Anagnostopoulos Athanasios K, Billinis Charalambos, Barbagianni Mariana S, Vasileiou Natalia G C, Spanos Stavros A, Mavrogianni Vasia S, Fthenakis George C
Veterinary Faculty, University of Thessaly, 43100 Karditsa, Greece.
Proteomics Research Unit, Biomedical Research Foundation of Academy of Athens, 11527 Athens, Greece.
Data Brief. 2019 Jul 16;25:104259. doi: 10.1016/j.dib.2019.104259. eCollection 2019 Aug.
Proteomics data have been obtained from experimental mastitis in ewes after intramammary challenge with . Animals were sampled before and sequentially after challenge; blood plasma and milk whey samples were produced and were subjected to proteomics evaluation by means of two-dimensional gel electrophoresis and MALDI-TOF mass spectrometry. Full protein maps and differential proteomics in sequential samples from blood plasma and milk whey of experimental ewes were presented. Post-challenge, 33 and 89 proteins were identified with differential abundance in blood plasma and milk whey, respectively. Also, 74 proteins were identified with differential abundance between the inoculated and contralateral glands. The data provide further insight in the pathogenesis of mastitis in sheep and indicate potential biomarkers for the disease. The data are further discussed in the research article "Differential quantitative proteomics study of experimental mastitis in sheep" [1].
在对母羊进行乳房内接种 后，已从实验性乳腺炎中获取了蛋白质组学数据。在接种前和接种后按顺序对动物进行采样；制备血浆和乳清样品，并通过二维凝胶电泳和基质辅助激光解吸电离飞行时间质谱法对其进行蛋白质组学评估。展示了来自实验母羊血浆和乳清的连续样品中的完整蛋白质图谱和差异蛋白质组学。接种后，分别在血浆和乳清中鉴定出33种和89种丰度有差异的蛋白质。此外，在接种腺体和对侧腺体之间鉴定出74种丰度有差异的蛋白质。这些数据为绵羊乳腺炎的发病机制提供了进一步的见解，并指出了该疾病的潜在生物标志物。研究文章《绵羊实验性乳腺炎的差异定量蛋白质组学研究》[1]中对这些数据进行了进一步讨论。
