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对 2017 年诺贝尔生理学或医学奖与中医的反思。

A Reflection on the 2017 Nobel Prize for Physiology and Chinese Medicine.

机构信息

Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.

Department of Chinese Medicine Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032, China.

出版信息

Chin J Integr Med. 2020 Nov;26(11):867-872. doi: 10.1007/s11655-018-2945-3. Epub 2019 Aug 5.

Abstract

Research on the molecular mechanisms controlling circadian rhythm in Western medicine is comparable to the study of a day-night rhythm in Chinese medicine (CM), as also focus on the same life phenomenon. By comparing the two, this paper elaborates on the differences between them in their respective issues of consciousness, ways of thinking, research methods and research results. Relatively speaking, Nobel Prize research has a stronger sense of the problems and concerns about the essence of "what", while CM focuses on "how a thing functions". The former mainly adopts experimental and mathematical methods, while the latter primarily depends on observation and understanding. The natural philosophy and natural science eventually lead to the results and the inevitable, quantitative and qualitative differences. Research on the life rhythm in CM should be proposed, scientific problems should be fully grasped, and research should be carried out with the aid of multidisciplinary new knowledge and new achievements through cross-disciplinary studies. On the basis of clinical epidemiological research and experimental research, a systematic review should be made of the human physiology of CM and the pathological rhythm model to explore the regulatory mechanism of time rhythm and create a new theory of time medicine.

摘要

西医对控制生物钟的分子机制的研究与中医(CM)对昼夜节律的研究相似,也关注同一生命现象。通过比较两者,本文阐述了它们在意识、思维方式、研究方法和研究结果等方面的差异。相对而言,诺贝尔奖研究对“是什么”的本质问题和关注更强烈,而 CM 则侧重于“事物如何运作”。前者主要采用实验和数学方法,而后者主要依赖于观察和理解。自然哲学和自然科学最终导致了结果的必然性、定量和定性的差异。CM 生命节律的研究应提出,要充分把握科学问题,通过跨学科研究借助多学科新知识和新成果开展研究。在临床流行病学研究和实验研究的基础上,对 CM 的人体生理学和病理节律模型进行系统评价,探索时间节律的调节机制,创造新的时间医学理论。

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