Department of Biology and Program in Neuroscience and Cognitive Science, University of Maryland, College Park, Maryland 20742, USA; email:
Annu Rev Vis Sci. 2019 Sep 15;5:451-477. doi: 10.1146/annurev-vision-091718-014731. Epub 2019 Aug 6.
With modern neurophysiological methods able to record neural activity throughout the visual pathway in the context of arbitrarily complex visual stimulation, our understanding of visual system function is becoming limited by the available models of visual neurons that can be directly related to such data. Different forms of statistical models are now being used to probe the cellular and circuit mechanisms shaping neural activity, understand how neural selectivity to complex visual features is computed, and derive the ways in which neurons contribute to systems-level visual processing. However, models that are able to more accurately reproduce observed neural activity often defy simple interpretations. As a result, rather than being used solely to connect with existing theories of visual processing, statistical modeling will increasingly drive the evolution of more sophisticated theories.
随着现代神经生理学方法能够在任意复杂的视觉刺激背景下记录整个视觉通路的神经活动,我们对视觉系统功能的理解正受到可用的视觉神经元模型的限制,这些模型可以直接与这些数据相关联。现在,不同形式的统计模型正被用于探究塑造神经活动的细胞和电路机制,理解如何计算神经对复杂视觉特征的选择性,并得出神经元对系统水平视觉处理的贡献方式。然而,能够更准确地再现观察到的神经活动的模型往往难以进行简单的解释。因此,统计建模不仅用于与现有的视觉处理理论联系,还将越来越多地推动更复杂理论的发展。